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Gene · 3045

HBD: hemoglobin subunit delta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HBD: hemoglobin subunit delta. Genes, record 3045. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3045

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Gene

Symbol
HBD
HGNC
Name
hemoglobin subunit delta
HGNC
NCBI Gene ID
3045
NCBI Gene
HGNC ID
HGNC:4829
HGNC
Ensembl
ENSG00000223609
NCBI Gene
Aliases
HBK
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P02042Hemoglobin subunit delta1472Ensembl, GeneID, HGNC

Source UniProt

Patents73

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448889P02042Espacenet
EP 4640849 A22025-10-293984P02042Espacenet
EP 4641201 A22025-10-2924817P02042Espacenet
JP 2025529142 A2025-09-041914P02042Espacenet
US 12371689 B22025-07-291914P02042Espacenet
JP 2025519096 A2025-06-243984P02042Espacenet
JP 2025517969 A2025-06-1224817P02042Espacenet
US 11834668 B22023-12-0515P02042Espacenet
US 11446398 B22022-09-2037719P02042Espacenet
US 11400027 B22022-08-0210P02042Espacenet

1 to 10 of 73

See all 73 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants376

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHBD papersNewest fiscal year
P20GM109021The Delaware Comprehensive Sickle Cell Research Center22025
P30CA023108Cancer Center Support Grant22025
P30DK026743UCSF Liver Center22025
R01HL119479Regulation of Hemoglobin Switching22025
T32AI007363Immunobiology of Myeloid and Lymphoid Cells22025
U54DK106829Stem Cell and Transplantation Biology22025
ZIAHL002338Genetic Modification and Novel Cell Therapies in Non-Human Primate Hematopoietic Cells22025
P01HL158507Scientific innovation for personalized severe asthma management12025
P20GM103446Delaware INBRE12025
P30AG066468Alzheimer Disease Research Center12025

1 to 10 of 376Source NIH's project files

See all 376 nih grants

Papers808

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Microcytic Anemia with Low HbA2 and Normal HbA: Two Cases of Rare Thalassemia.Hemoglobin202642655983PubTator, text miningPubMed
Genetic Analysis of Two Patients with Compound Thalassemia Presenting with Elevated HbF and Normal HbA2 Levels.Hemoglobin202642509210PubTator, text miningPubMed
Short-term maternal outcomes after intraoperative administration of prophylactic oxytocin during cesarean sections: a retrospective cohort study with a comparison of different administration protocols.
Arch Gynecol Obstet202641902958PubTator, text miningPubMed
A novel HBD gene mutation associated with normal-range hb A2 in β-thalassemia carriers.Ann Hematol202641765964PubTator, text miningPubMed
The Mystery of the Hidden Trace: Emerging Genetic Approaches to Improve Body Fluid Identification.Genes (Basel)202641751530PubTator, text miningPubMed
The impact of the expression signatures of LncRNAs HBBP1 and XIST on the diagnostic significance of patients with β-Thalassemia.Ann Hematol202641634383PubTator, text miningPubMed
Two Novel δ-Globin Chain Variants Identified in the Chinese Population.Hemoglobin202641508683PubTator, text miningPubMed
IFN-γ increases δ-globin gene expression through activation of the JAK/STAT pathway in erythroid cells.Blood202641284617PubTator, text miningPubMed
From anonymity to stardom: history of nontuberculous mycobacterial disease in humans.Front Cell Infect Microbiol202541808770PubTator, text miningPubMed
The Masked Thalassemia: A Rare Case of a Patient with Normal HbA2 Levels, β-Thalassemia Pathogenic Variant (CD39 C>T), and a Novel δ-Globin Gene Deletion.Appl Clin Genet202541255956PubTator, text miningPubMed

1 to 10 of 808

See all 808 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3045

GET https://conductscience.org/api/genes/v1/3045/patents?page=2