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Gene · 3061

Papers869

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Thymosin Alpha-1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis.Adv Sci (Weinh)202642693587PubTator, text miningPubMed
Beyond traditional sleeping pills: safety, efficacy and multidisease potential of three approved orexin receptor antagonists.Front Psychiatry202642683191PubTator, text miningPubMed
Research Progress and Future Perspectives of Orexin Receptor Antagonists in Insomnia Therapy.Molecules202642653878PubTator, text miningPubMed
The orexin system as a pharmacological target in inflammation: peripheral mechanisms and safety implications.Front Pharmacol202642609337PubTator, text miningPubMed
Probing chemical space and conformational changes for subtype-selective orexin receptor antagonists.RSC Med Chem202642592024PubTator, text miningPubMed
Involvement of the cannabinoid receptors of the basolateral amygdala in the orexin A-mediated modulation of the stress-induced analgesia.Neuropharmacology202642526687PubTator, text miningPubMed
Lateral hypothalamic orexinergic neurons as central mediators of pain modulation and non-pharmacological analgesia.Front Pharmacol202642460012PubTator, text miningPubMed
A Scoping Review of Orexin Antagonists in Post-Traumatic Stress Disorder: Modulating Sleep, Stress, and Fear Circuits.Mil Med202642391109PubTator, text miningPubMed
A Dimer for Dinner: The Impact of GHS-R1a Heterodimerization on Feeding Circuits.Biomolecules202642352256PubTator, text miningPubMed
The orexinergic system in the retina: Expression and physiological impact-A review of the literature.Front Neuroendocrinol202642150720PubTator, text miningPubMed
The impacts of trauma and stress on orexin expression and signalling: A systematic review.Psychiatry Res202642134275PubTator, text miningPubMed
Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors.Acta Crystallogr F Struct Biol Commun202642059114PubTator, text miningPubMed
Physiological significance of autocrine orexinergic signaling in extra-hypothalamic tissues.Physiol Rep202642033055PubTator, text miningPubMed
Neuroendocrine Control of the Testis: Focus on Orexinergic Modulation of Spermatogenesis.J Comp Neurol202641980893PubTator, text miningPubMed
Incretin-Based Therapies: A Novel Pathway in Addiction Treatment.J Clin Med202641753300PubTator, text miningPubMed
The Intersection of m6A Methylation and Immune Response in PCOS: A Bioinformatics Perspective.Immun Inflamm Dis202641725222PubTator, text miningPubMed
Orexin signaling across the female lifespan: developmental, reproductive, and aging perspectives from humans and animal models.Front Neuroendocrinol202641690524PubTator, text miningPubMed
The Role of Danavorexton for Perioperative Opioid-Induced Respiratory Depression and Sedation: A Narrative Review.Clin Pharmacol202641555862PubTator, text miningPubMed
Differential modulation of contextual fear conditioning by orexin receptors in the dorsal hippocampus.Behav Brain Res202641455586PubTator, text miningPubMed
Orexinergic pathway as a potential therapeutic candidate for the modulation of glucose homeostasis.Front Physiol202541438219PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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