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Gene · 3067

HDC: histidine decarboxylase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HDC: histidine decarboxylase. Genes, record 3067. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3067

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Gene

Symbol
HDC
HGNC
Name
histidine decarboxylase
HGNC
NCBI Gene ID
3067
NCBI Gene
HGNC ID
HGNC:4855
HGNC
Ensembl
ENSG00000140287
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P19113Histidine decarboxylase6624Ensembl, GeneID, HGNC

Source UniProt

Patents14

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449126P19113Espacenet
EP 4641201 A22025-10-292215P19113Espacenet
EP 4641202 A22025-10-294615P19113Espacenet
JP 2025517969 A2025-06-122215P19113Espacenet
KR 1020250017231 A2025-02-044615P19113Espacenet
US 11446398 B22022-09-2038401P19113Espacenet
JP 2022524081 A2022-04-27141372P19113Espacenet
US 11078247 B22021-08-034912P19113Espacenet
JP 2019054813 A2019-04-11229561P19113Espacenet
JP 2017121241 A2017-07-13229561P19113Espacenet

1 to 10 of 14

See all 14 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants926

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHDC papersNewest fiscal year
R25MH077823Research Education for Future Physician-Scientists in Child Psychiatry112025
P30DK056338Texas Medical Center Digestive Diseases Center82025
UL1TR001863Yale Clinical and Translational Science Award82025
IK6BX004601BLR&D Research Career Scientist Award62025
P30CA013696Cancer Center Support Grant42025
P30DK132710The Columbia University Digestive and Liver Disease Research Center32025
T32AI007306Immunologic Basis of Resistance and Hypersensitivity32025
U19AG063893The Long Life Family Study32025
K24AG053435Neuropathological changes underlying clinical heterogeneity in Alzheimer disease22025
P20GM109036Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases22025

1 to 10 of 926Source NIH's project files

See all 926 nih grants

Papers2,844

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Xianling Gubao Capsule for Osteoporosis: A Review of Active Components and Underlying Mechanisms.Curr Protein Pept Sci202642816999PubTator, text miningPubMed
Brucellar spondylitis is associated with disturbance in gut microbiota and histamine metabolism associated inflammation.Front Cell Infect Microbiol202642723989PubTator, text miningPubMed
The potential role of aberrant microglial synaptic pruning in the neurodevelopmental pathogenesis of tourette syndrome.Front Neurosci202642487691PubTator, text miningPubMed
Time-Resolved Multi-Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination.Allergy202642466809PubTator, text miningPubMed
A Convenient and Economical Spectrophotometric Assay for Ornithine Decarboxylase and Related Amino Acid Decarboxylases Using Sodium 2,4-Dinitrobenzenesulfonate.ACS Omega202642368114PubTator, text miningPubMed
Redox-sensitive GPCR signaling drives Gq-dependent Ca2+ mobilization and cytokine production in human bronchial epithelial cells.Am J Physiol Cell Physiol202642314770PubTator, text miningPubMed
The role of histidine metabolism in tumor progression and its clinical significance.Biochem Biophys Res Commun202642284986PubTator, text miningPubMed
Myeloid Cell-Derived Thrombospondin-1 Mediates Anti-Metastatic Effects of Histamine Dihydrochloride in B16 Melanoma.Immunotargets Ther202642281617PubTator, text miningPubMed
Multi-omics Mendelian randomization integrating metabolism, microbiome and immunity supports a putative gut-immune-pelvic pathway in deep infiltrating endometriosis.Front Endocrinol (Lausanne)202642255437PubTator, text miningPubMed
Transcriptomic Determinants of Circulating Immunity Predict Immune-Related Adverse Events (irAEs) in Cancer Patients Receiving PD-1/PD-L1 Blockade.Thorac Cancer202641920053PubTator, text miningPubMed

1 to 10 of 2,844

See all 2,844 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3067

GET https://conductscience.org/api/genes/v1/3067/patents