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CFH: complement factor H

1 protein, 190 patents, 0 drugs, 0 trials, 4,448 NIH grants and 10,693 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCFHHGNC
Namecomplement factor HHGNC
NCBI Gene ID3075NCBI Gene
HGNC IDHGNC:4883HGNC
EnsemblENSG00000000971NCBI Gene
AliasesAHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUSNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P08603Complement factor H1,23151Ensembl, GeneID, HGNCUniProt

Patents 190

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026120564 A2026-07-224P08603Espacenet
JP 2026515744 A2026-05-1943P08603Espacenet
EP 4731771 A12026-04-2963P08603Espacenet
JP 2026067851 A2026-04-21394P08603Espacenet
EP 4714979 A12026-03-253P08603Espacenet
JP 2026053563 A2026-03-259P08603Espacenet
JP 2026041876 A2026-03-103P08603Espacenet
US 12544423 B22026-02-1029P08603Espacenet
JP 2026501750 A2026-01-1639P08603Espacenet
WO 2025253101 A12025-12-1116P08603Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4448

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30EY014800University of Utah Core Vision Research Grant322,025NIH's project files
P30EY005722Center Core Grant for Vision Research282,025NIH's project files
R01DK076690Complement-mediated injury of the kidney: New mechanisms and novel therapies262,025NIH's project files
ZIAEY000489Age-Related Eye Disease Follow-up Study (AREDS) Follow-up Study262,025NIH's project files
ZIAEY000546Mechanisms, modeling and therapies of retinal and macular neurodegeneration222,025NIH's project files
R01AR051749Complement in the Pathogenesis of Autoimmune Arthritis192,025NIH's project files
R01DK110023C3 Glomerulopathy -- A Collaborative Study192,025NIH's project files
P30EY014801Miami Center for Vision Research182,025NIH's project files
R01HL076179Improvement of Organ Function after Severe Hypovolemia162,025NIH's project files
P30EY014104P30 Core Grant for Vision Research152,025NIH's project files

Papers 10693

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821580PubTator, text miningPubMed
42794833PubTator, text miningPubMed
42792836PubTator, text miningPubMed
42780117PubTator, text miningPubMed
42779682PubTator, text miningPubMed
42777977PubTator, text miningPubMed
42762750PubTator, text miningPubMed
42746023PubTator, text miningPubMed
42742155PubTator, text miningPubMed
42737716PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license