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Gene · 3078

CFHR1: complement factor H related 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CFHR1: complement factor H related 1. Genes, record 3078. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3078

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Gene

Symbol
CFHR1
HGNC
Name
complement factor H related 1
HGNC
NCBI Gene ID
3078
NCBI Gene
HGNC ID
HGNC:4888
HGNC
Ensembl
ENSG00000244414
NCBI Gene
Aliases
CFHL, CFHL1, CFHL1P, CFHR1P, FHL-1, FHR-1, FHR1, H36, H36-1, H36-2, HFL1, HFL2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q03591Complement factor H-related protein 13302Ensembl, GeneID, HGNC

Source UniProt

Patents53

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442125Q03591Espacenet
EP 4650780 A22025-11-194949Q03591Espacenet
EP 4641201 A22025-10-294525Q03591Espacenet
JP 2025147176 A2025-10-062690Q03591Espacenet
JP 2025529142 A2025-09-045843Q03591Espacenet
US 12371689 B22025-07-295843Q03591Espacenet
JP 2025517969 A2025-06-124525Q03591Espacenet
JP 2025517970 A2025-06-124949Q03591Espacenet
JP 2025028160 A2025-02-282690Q03591Espacenet
EP 4505469 A22025-02-1244Q03591Espacenet

1 to 10 of 53

See all 53 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants843

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCFHR1 papersNewest fiscal year
R01DK110023C3 Glomerulopathy -- A Collaborative Study102025
P30EY014800University of Utah Core Vision Research Grant52025
R01DK078244Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes52025
R01AR051749Complement in the Pathogenesis of Autoimmune Arthritis42025
P30EY014801Miami Center for Vision Research32025
R01HG002385Long-read sequence and assembly of segmental duplications32025
T32HL007344Program in Hematology: Molecular & Cell Biology of Blood Cells32025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA046934University of Colorado Cancer Center Support Grant22025
P30ES005605Environmental Health Sciences Research Center22025

1 to 10 of 843Source NIH's project files

See all 843 nih grants

Papers1,634

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Kidney transplant outcomes in patients with complement dysregulation.World J Transplant202642751233PubTator, text miningPubMed
TM184C is a GPCR-like regulator of intercellular exchange and autophagy.Nature202642717083PubTator, text miningPubMed
Normoalbuminuric and albuminuric diabetic kidney disease exhibit divergent renal proteomic characteristics: implications for management.Diabetes Res Clin Pract202642648547PubTator, text miningPubMed
Integrated Bulk and Spatial Proteomics of Castleman Disease: Molecular Signatures Across Subtypes and Compartmentalized Pathogenic Networks in Idiopathic Multicentric Castleman disease (iMCD)-Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Dysfunction, and Organomegaly (TAFRO).
Mod Pathol202642641686PubTator, text miningPubMed
Complement-related genetic analysis for Japanese children with transplant-associated thrombotic microangiopathy.Front Pediatr202642553292PubTator, text miningPubMed
Extended haplotypes at the complement factor H gene locus are associated with liver transplant rejection.Hepatol Commun202642486812PubTator, text miningPubMed
Identification and functional validation of lactylation-related hub genes in idiopathic pulmonary fibrosis based on multi-omics analysis.Respir Res202642400038PubTator, text miningPubMed
Multi-omics triangulation identifies complement factor H as a genetically supported protective factor in IgA nephropathy.Clin Kidney J202642389194PubTator, text miningPubMed
Predictive biomarkers of COVID-19 impact in renal transplant patients: an exploratory proteomic and cytokine analysis.Front Immunol202642367818PubTator, text miningPubMed
Fetal heart rate and the neonatal QT interval: Results from a large general population study.Heart Rhythm O2202642183001PubTator, text miningPubMed

1 to 10 of 1,634

See all 1,634 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3078

GET https://conductscience.org/api/genes/v1/3078/patents?page=2