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Gene · 3087

HHEX: hematopoietically expressed homeobox

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HHEX: hematopoietically expressed homeobox. Genes, record 3087. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3087

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Gene

Symbol
HHEX
HGNC
Name
hematopoietically expressed homeobox
HGNC
NCBI Gene ID
3087
NCBI Gene
HGNC ID
HGNC:4901
HGNC
Ensembl
ENSG00000152804
NCBI Gene
Aliases
HEX, HMPH, HOX11L-PEN, PRH, PRHX
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q03014Hematopoietically-expressed homeobox protein HHEX2701Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448870Q03014Espacenet
EP 4641201 A22025-10-292742Q03014Espacenet
JP 2025147176 A2025-10-0615081Q03014Espacenet
JP 2025517969 A2025-06-122742Q03014Espacenet
JP 2025028160 A2025-02-2815081Q03014Espacenet
EP 4504906 A22025-02-123Q03014Espacenet
EP 4504907 A22025-02-126Q03014Espacenet
KR 1020250010750 A2025-01-2115081Q03014Espacenet
EP 4484957 A12025-01-01197Q03014Espacenet
KR 1020240169086 A2024-12-026Q03014Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,453

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHHEX papersNewest fiscal year
P30CA008748Cancer Center Support Grant162025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION112025
ZIAHG000024Genetic analysis of type II diabetes112025
P30DK020572Michigan Diabetes Research Center (MDRC)102025
P30DK063491Diabetes Research Center (DRC)102025
P30CA016672Cancer Center Support Grant92025
R01CA080728Oncogenic Impact of eIF4E-dependent RNA Export in Cancer92025
R01CA098571Molecular Mechanisms of eIF4E Mediated Transformation72025
P30CA015704Cancer Center Support Grant62025
P30CA021765Cancer Center Support Grant (CCSG)62025

1 to 10 of 2,453Source NIH's project files

See all 2,453 nih grants

Papers3,439

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genetic variation in HLA, IGKV, and HHEX loci influences mRNA vaccine-induced humoral protection against COVID-19.Cell Rep202642814572PubTator, text miningPubMed
Genetically engineered porcine liver: a new era in transplantation.Int J Surg202642808109PubTator, text miningPubMed
Assessment of 226Ra, 232Th and 40K in soil with gamma dose rates from quarries of the Mandya district, Karnataka, India.Environ Geochem Health202642762347PubTator, text miningPubMed
Multiscale structural evolution of proline-rich protein genes shapes primate salivary defenses.Mol Biol Evol202642671077PubTator, text miningPubMed
A Phototheranostic Probe Activated by β-N-Acetylhexosaminidase for Fluorescence Navigation Surgery and Photodynamic Therapy of Colorectal Cancer.Adv Healthc Mater202642596506PubTator, text miningPubMed
Cortisol Drives Pregnancy-Associated Induction of Hepatic OAT2, NTCP, and OCT1 in HepaRG cells Through GR-, HNF1α-, and HNF4α-Dependent Signaling.bioRxiv202642367899PubTator, text miningPubMed
Single-cell landscape of goose thymus uncovers developmental and regulatory dynamics of T cell differentiation.Poult Sci202642061246PubTator, text miningPubMed
Damaging the conical morphology of HIV-1 capsid by targeting the FG-binding pocket and disfavoring pentameric subunits needed for core closure.bioRxiv202641889801PubTator, text miningPubMed
Examining Epigenetic Age in Women with Different Obesity Conditions Using DNA Methylation at the FHL2 Gene.Methods Protoc202641874164PubTator, text miningPubMed
Fatty acid oxidation drives acetyl-CoA-dependent H3K9ac reprogramming to promote adaptive resistance to BRAFV600E inhibition in thyroid cancer.Cell Death Dis202641862440PubTator, text miningPubMed

1 to 10 of 3,439

See all 3,439 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3087

GET https://conductscience.org/api/genes/v1/3087/patents?page=2