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Gene · 3090

HIC1: HIC ZBTB transcriptional repressor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HIC1: HIC ZBTB transcriptional repressor 1. Genes, record 3090. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3090

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Gene

Symbol
HIC1
HGNC
Name
HIC ZBTB transcriptional repressor 1
HGNC
NCBI Gene ID
3090
NCBI Gene
HGNC ID
HGNC:4909
HGNC
Ensembl
ENSG00000177374
NCBI Gene
Aliases
ZBTB29, ZNF901, hic-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14526Hypermethylated in cancer 1 protein7330Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194941Q14526Espacenet
EP 4641201 A22025-10-294519Q14526Espacenet
EP 4641202 A22025-10-294888Q14526Espacenet
JP 2025147176 A2025-10-0615082Q14526Espacenet
JP 2025517969 A2025-06-124519Q14526Espacenet
JP 2025517970 A2025-06-124941Q14526Espacenet
JP 2025028160 A2025-02-2815082Q14526Espacenet
KR 1020250017231 A2025-02-044888Q14526Espacenet
KR 1020250010750 A2025-01-2115082Q14526Espacenet
JP 2024123008 A2024-09-106524Q14526Espacenet

1 to 10 of 26

See all 26 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants852

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHIC1 papersNewest fiscal year
P30CA006973Regional Oncology Research Center52025
P30CA016672Cancer Center Support Grant52025
P01CA096832NORMAL & NEOPLASTIC GROWTH IN THE BRAIN32025
P30CA008748Cancer Center Support Grant32025
P30CA033572Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025
P30ES001247Environmental Agents as Modulators of Disease Processes32025
T32CA009560Carcinogenesis Training Program32025
ZIALM200881Regulatory landscape of the human genome: comparative and evolutionary analysis.32025
P30CA013330Cancer Center Support Grant22025

1 to 10 of 852Source NIH's project files

See all 852 nih grants

Papers1,365

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
DNA methylation biomarkers for early detection of ovarian cancer.Mol Biol Rep202642726150PubTator, text miningPubMed
Proteomic Insights Into Human Induced Regulatory T Cells: The Role of LPXN and CD160 in Immune Suppression.Mol Cell Proteomics202642624209PubTator, text miningPubMed
Mechanosensing by T cells promotes a tissue-resident memory transcriptional program.Nat Immunol202642399696PubTator, text miningPubMed
Myotendinous Junction development and repair.J Orthop Translat202642088570PubTator, text miningPubMed
Spatial single cell transcriptomic analysis informs tumor developmental hierarchy of DICER1 syndrome related sarcoma.Nat Commun202641912509PubTator, text miningPubMed
Identification of biomarkers associated with endoplasmic reticulum stress-related cell death in osteoporosis based on bulk and single-cell transcriptomic analyses and experimental validation.Sci Rep202641905994PubTator, text miningPubMed
Exosomes in diabetic kidney disease: pathogenesis, biomarker discovery, and emerging therapeutics-a comprehensive systematic review.Ren Fail202641845912PubTator, text miningPubMed
AmalgaMo: flexible DNA motif merging.Bioinform Adv202641768281PubTator, text miningPubMed
Microglial heterogeneity: influence of human 2D, 3D, and co-culture models on gene expression and immune function.Front Cell Neurosci202641757348PubTator, text miningPubMed
Chromatin Remodeling in VSMC Phenotype Switching During Vascular Remodeling: From Mechanism to Therapeutic Potential.Biomolecules202641750335PubTator, text miningPubMed

1 to 10 of 1,365

See all 1,365 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3090

GET https://conductscience.org/api/genes/v1/3090/patents?page=2