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Gene · 3093

UBE2K: ubiquitin conjugating enzyme E2 K

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. UBE2K: ubiquitin conjugating enzyme E2 K. Genes, record 3093. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3093

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Gene

Symbol
UBE2K
HGNC
Name
ubiquitin conjugating enzyme E2 K
HGNC
NCBI Gene ID
3093
NCBI Gene
HGNC ID
HGNC:4914
HGNC
Ensembl
ENSG00000078140
NCBI Gene
Aliases
E2-25K, HIP2, HYPG, LIG, UBC1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P61086Ubiquitin-conjugating enzyme E2 K20013Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191891P61086Espacenet
JP 2025517970 A2025-06-121891P61086Espacenet
JP 2025003968 A2025-01-141P61086Espacenet
JP 2023550743 A2023-12-0584P61086Espacenet
JP 2023504790 A2023-02-0716P61086Espacenet
US 11564998 B22023-01-314895P61086Espacenet
US 11446398 B22022-09-2095238P61086Espacenet
JP 2022524081 A2022-04-27198209P61086Espacenet
JP 2022500378 A2022-01-042P61086Espacenet
JP 2021525807 A2021-09-2712P61086Espacenet

1 to 10 of 44

See all 44 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,613

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUBE2K papersNewest fiscal year
R01GM065334Solution structure and dynamics of polyubiquitin chains142025
P01CA092584Structural Cell Biology of DNA Repair Machines112025
R01HD059205Interventions in math learning disabilities: cognitive and neural correlates102025
R01ES012512Roles of Lig3 and XRCC1 Genes in Genome Stability82025
P30CA016672Cancer Center Support Grant72025
P30CA008748Cancer Center Support Grant62025
P30CA118100University of New Mexico Cancer Center Support Grant62025
P20GM103440Nevada IDeA Networks of Biomedical Research Excellence (INBRE)42025
P30CA016058Cancer Center Support Grant42025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions32025

1 to 10 of 1,613Source NIH's project files

See all 1,613 nih grants

Papers3,161

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction: Ubiquitin-protein ligase E3C promotes glioma progression by mediating the ubiquitination and degrading of Annexin A7.Sci Rep202642744935PubTator, text miningPubMed
[Ubiquitination-mediated regulation of T cell homeostasis and autoimmune diseases].Zhong Nan Da Xue Xue Bao Yi Xue Ban202642702386PubTator, text miningPubMed
Disruption of the ubiquitin-mediated proteolysis pathway: a study of seed aging in Saposhnikovia divaricata caused by UBC1 gene family suppression.BMC Plant Biol202642337438PubTator, text miningPubMed
Porcine Reproductive and Respiratory Syndrome Virus NSP8 Suppresses NF-κB Signaling by Hijacking Host UBE2K and IKKα.Viruses202642198770PubTator, text miningPubMed
SNRPD2-CPSF7-UBE2K axis drives ovarian cancer progression via alternative splicing-polyadenylation crosstalk.Oncogene202642098443PubTator, text miningPubMed
CXCR4 coordinates adhesion, migration, and development of human NK cells.bioRxiv202642051299PubTator, text miningPubMed
Insight into the potential significance of miR-760 and miR-1973 in breast cancer: a comprehensive analysis.Sci Rep202641922567PubTator, text miningPubMed
North American ice sheet persistence into past interglacials should inform future projections.Nat Commun202641792116PubTator, text miningPubMed
Dual targeting of the UPS and autophagy as a novel therapy for neurodegenerative proteinopathies.Front Cell Neurosci202641788195PubTator, text miningPubMed
Combining Laser-Induced Graphene with Kirigami for Transparent Flexible Electromagnetic Interference Shielding.ACS Appl Eng Mater202641783240PubTator, text miningPubMed

1 to 10 of 3,161

See all 3,161 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3093

GET https://conductscience.org/api/genes/v1/3093/patents?page=2