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HLA-A: major histocompatibility complex, class I, A

1 protein, 113 patents, 0 drugs, 0 trials, 21,603 NIH grants and 91,008 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHLA-AHGNC
Namemajor histocompatibility complex, class I, AHGNC
NCBI Gene ID3105NCBI Gene
HGNC IDHGNC:4931HGNC
EnsemblENSG00000206503NCBI Gene
AliasesHLAANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P04439HLA class I histocompatibility antigen, A alpha chain365403Ensembl, GeneID, HGNCUniProt

Patents 113

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4801948 A12026-09-0943P04439Espacenet
EP 4753743 A12026-06-101P04439Espacenet
JP 2026516062 A2026-05-1999P04439Espacenet
JP 2026515163 A2026-05-1416P04439Espacenet
EP 4709744 A12026-03-1899P04439Espacenet
EP 4650780 A22025-11-199834P04439Espacenet
EP 4640849 A22025-10-291496P04439Espacenet
EP 4641201 A22025-10-2910092P04439Espacenet
JP 2025147176 A2025-10-066487P04439Espacenet
JP 2025147176 A2025-10-066489P04439Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 21603

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant5282,025NIH's project files
U24CA076518A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research3292,025NIH's project files
P30CA016672Cancer Center Support Grant2772,025NIH's project files
P01CA018029Adult Leukemia Research Center2692,025NIH's project files
P30CA015704Cancer Center Support Grant2202,025NIH's project files
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies1312,025NIH's project files
ZIABC010791Effects of genetic polymorphism in MHC, KIR, and related loci on human disease1152,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award1082,025NIH's project files
P30CA006973Regional Oncology Research Center1062,025NIH's project files
P30AI060354Harvard University Center for AIDS Research1052,025NIH's project files

Papers 91008

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826859PubTator, text miningPubMed
42825917PubTator, text miningPubMed
42825120PubTator, text miningPubMed
42820749PubTator, text miningPubMed
42820302PubTator, text miningPubMed
42820290PubTator, text miningPubMed
42819770PubTator, text miningPubMed
42819744PubTator, text miningPubMed
42818707PubTator, text miningPubMed
42818344PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license