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HLA-C: major histocompatibility complex, class I, C

1 protein, 78 patents, 0 drugs, 0 trials, 24,228 NIH grants and 65,190 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHLA-CHGNC
Namemajor histocompatibility complex, class I, CHGNC
NCBI Gene ID3107NCBI Gene
HGNC IDHGNC:4933HGNC
EnsemblENSG00000204525NCBI Gene
AliasesD6S204, HLA-JY3, HLAC, HLC-C, MHC, PSORS1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P10321HLA class I histocompatibility antigen, C alpha chain36613Ensembl, GeneID, HGNCUniProt

Patents 78

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4801948 A12026-09-0945P10321Espacenet
JP 2026515163 A2026-05-1419P10321Espacenet
EP 4650780 A22025-11-199745P10321Espacenet
EP 4640849 A22025-10-291475P10321Espacenet
EP 4641201 A22025-10-299999P10321Espacenet
JP 2025147176 A2025-10-066493P10321Espacenet
JP 2025529142 A2025-09-041958P10321Espacenet
JP 2025529142 A2025-09-046596P10321Espacenet
US 12371689 B22025-07-291958P10321Espacenet
US 12371689 B22025-07-296596P10321Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 24228

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant3402,025NIH's project files
P30CA016672Cancer Center Support Grant2032,025NIH's project files
P01CA018029Adult Leukemia Research Center1162,025NIH's project files
U24CA076518A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research1112,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award992,025NIH's project files
P30CA015704Cancer Center Support Grant932,025NIH's project files
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro772,025NIH's project files
ZIABC010791Effects of genetic polymorphism in MHC, KIR, and related loci on human disease752,025NIH's project files
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies692,025NIH's project files
P51OD011132Emory National Primate Research Center672,025NIH's project files

Papers 65190

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824087PubTator, text miningPubMed
42822865PubTator, text miningPubMed
42822443PubTator, text miningPubMed
42821042PubTator, text miningPubMed
42815647PubTator, text miningPubMed
42814277PubTator, text miningPubMed
42814220PubTator, text miningPubMed
42808769PubTator, text miningPubMed
42804096PubTator, text miningPubMed
42802494PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license