ConductScience.org, home

Gene · 3113

HLA-DPA1: major histocompatibility complex, class II, DP alpha 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. HLA-DPA1: major histocompatibility complex, class II, DP alpha 1. Genes, record 3113. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3113

On this page

Gene

Symbol
HLA-DPA1
HGNC
Name
major histocompatibility complex, class II, DP alpha 1
HGNC
NCBI Gene ID
3113
NCBI Gene
HGNC ID
HGNC:4938
HGNC
Ensembl
ENSG00000231389
NCBI Gene
Aliases
DP(W3), DP(W4), DPA1, HLA-DP1A, HLA-DPA, HLADP, HLASB, PLT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P20036HLA class II histocompatibility antigen, DP alpha 1 chain26010Ensembl, GeneID, HGNC

Source UniProt

Patents251

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4801948 A12026-09-0939P20036Espacenet
JP 2026501516 A2026-01-1623828P20036Espacenet
JP 2026004568 A2026-01-1452255P20036Espacenet
JP 2026004568 A2026-01-1452256P20036Espacenet
JP 2026004568 A2026-01-1452260P20036Espacenet
JP 2026004568 A2026-01-1452262P20036Espacenet
JP 2026004568 A2026-01-1452264P20036Espacenet
JP 2026004568 A2026-01-1452269P20036Espacenet
JP 2026004568 A2026-01-1452282P20036Espacenet
JP 2026004568 A2026-01-1452290P20036Espacenet

1 to 10 of 251

See all 251 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,839

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHLA-DPA1 papersNewest fiscal year
R01AR063759Defining the influence of RA genetic susceptibility factors on T cell antigen specificity and functional state92025
UL1TR001863Yale Clinical and Translational Science Award72025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital62025
U24CA076518A Data Resource for Blood and Marrow Transplants and Adoptive Cellular Therapy Research62025
ZIABC010791Effects of genetic polymorphism in MHC, KIR, and related loci on human disease62025
P30CA016672Cancer Center Support Grant52025
R01DK032083Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes52025
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro52025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)52025
P30CA015704Cancer Center Support Grant42025

1 to 10 of 1,839Source NIH's project files

See all 1,839 nih grants

Papers2,625

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
High-Resolution HLA Allele and Haplotype Frequencies in a Southern Brazilian Population.HLA202642806292PubTator, text miningPubMed
Tissue-specific recombination-activated clonal and inducible transcription (TRAC-IT) enables controlled gene activation in stably marked tissues.Plant J202642802906PubTator, text miningPubMed
Characterisation of the Novel HLA-DPA1*01:03:01:155Q Allele by Next-Generation Sequencing.HLA202642802484PubTator, text miningPubMed
Characterisation of the Novel HLA-DPA1*01:03:64 Allele by Sequencing-Based Typing.HLA202642754547PubTator, text miningPubMed
Identification of the Novel HLA-DPA1*01:258 Allele by Third-Generation Sequencing.HLA202642751983PubTator, text miningPubMed
Transcriptomic Signatures of Microglial Phagocytosis Reveal Diagnostic Markers and Immune Landscape in Alzheimer's Disease.FASEB J202642663999PubTator, text miningPubMed
Validation of Sequence-Specific Oligonucleotide Probe-Based HLA Homozygosity Classification Using 11-Locus Next-Generation Sequencing in Korean Cord Blood Units: Extended Haplotype Architecture and Implications for Induced Pluripotent Stem Cell Haplobanking.
Ann Lab Med202642661591PubTator, text miningPubMed
Characterisation of the HLA-DPA1*01:194:01:02 Allele by Next-Generation Sequencing.HLA202642658028PubTator, text miningPubMed
Investigating the Cellular Activity and Differential Gene Expression of Human Astrocytes in Interaction with Protein Composite Nanofibers.Neurochem Res202642599588PubTator, text miningPubMed
Integrating genomic structural equation modeling and experimental validation to unravel the genetic basis of male genital lichen sclerosus.Front Immunol202642553536PubTator, text miningPubMed

1 to 10 of 2,625

See all 2,625 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3113

GET https://conductscience.org/api/genes/v1/3113/patents?page=2