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Gene · 3131

HLF: HLF transcription factor, PAR bZIP family member

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HLF: HLF transcription factor, PAR bZIP family member. Genes, record 3131. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3131

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Gene

Symbol
HLF
HGNC
Name
HLF transcription factor, PAR bZIP family member
HGNC
NCBI Gene ID
3131
NCBI Gene
HGNC ID
HGNC:4977
HGNC
Ensembl
ENSG00000108924
NCBI Gene
Aliases
MGC33822
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16534Transcription factor HLF2950Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448945Q16534Espacenet
EP 4641201 A22025-10-29454Q16534Espacenet
JP 2025147176 A2025-10-0615091Q16534Espacenet
JP 2025517969 A2025-06-12454Q16534Espacenet
JP 2025028160 A2025-02-2815091Q16534Espacenet
KR 1020250010750 A2025-01-2115091Q16534Espacenet
JP 2024109657 A2024-08-1414930Q16534Espacenet
KR 1020240010752 A2024-01-24182Q16534Espacenet
JP 2023165849 A2023-11-17182Q16534Espacenet
US 11446398 B22022-09-2037794Q16534Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,194

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHLF papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)202025
P30CA016672Cancer Center Support Grant82025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia72025
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement62025
P30CA008748Cancer Center Support Grant52025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal52025
R01DK103794Systematic Genetic Dissection of Human Erythropoiesis42025
R01HL146500Next generation functional genomics of hematology traits42025
U10CA180899Children's Oncology Group Statistics and Data Center42025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)32025

1 to 10 of 1,194Source NIH's project files

See all 1,194 nih grants

Papers1,870

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Uncovering molecular and functional dynamics of human hematopoietic stem cells during in vitro culture for cell therapy manufacturing.Cytotherapy202642556173PubTator, text miningPubMed
A synchronous counter-positive strategy via online CE-SELEX for high-efficiency aptamer selection.J Chromatogr A202642176419PubTator, text miningPubMed
The inhibitory effect of hepatic cancer energy metabolism on immune checkpoint therapy: perspectives from single-cell multi-omics analysis.Front Immunol202642051493PubTator, text miningPubMed
From Residency to Tissue Inflammatory Memory: HLF as a Transcriptional Gatekeeper of CD4 + Tissue-Resident Memory T Cells.Respirology202642026931PubTator, text miningPubMed
Advances in the diagnosis and classification of B-ALL: comparative insights from updated guidelines.Blood Adv202641886641PubTator, text miningPubMed
Transient SUMOylation inhibition in human pre-adipocytes stably imprints a transcriptional beiging fate.Nucleic Acids Res202641854078PubTator, text miningPubMed
Lactoferrin blocks orthopoxvirus entry via heparan sulphate and regulates host antiviral pathways.Emerg Microbes Infect202641790953PubTator, text miningPubMed
Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans.bioRxiv202641726901PubTator, text miningPubMed
A review of treatment strategies for elderly patients with Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia.Transl Oncol202641690286PubTator, text miningPubMed
Single cell atlas decodes the molecular dynamics of scar repair after human rotator cuff tear.Bone Res202641644521PubTator, text miningPubMed

1 to 10 of 1,870

See all 1,870 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3131

GET https://conductscience.org/api/genes/v1/3131/patents?page=2