Gene · 3131
HLF: HLF transcription factor, PAR bZIP family member
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HLF: HLF transcription factor, PAR bZIP family member. Genes, record 3131. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3131
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16534 | Transcription factor HLF | 295 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents42
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48945 | Q16534 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 454 | Q16534 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15091 | Q16534 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 454 | Q16534 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15091 | Q16534 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15091 | Q16534 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 14930 | Q16534 | Espacenet |
| KR 1020240010752 A | 2024-01-24 | 182 | Q16534 | Espacenet |
| JP 2023165849 A | 2023-11-17 | 182 | Q16534 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 37794 | Q16534 | Espacenet |
1 to 10 of 42
See all 42 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,194
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HLF papers | Newest fiscal year |
|---|---|---|---|
| P30CA021765 | Cancer Center Support Grant (CCSG) | 20 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| R35CA197695 | Translating genomic discoveries to improved outcomes for high risk acute leukemia | 7 | 2025 |
| U10CA180886 | COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 5 | 2025 |
| R01DK103794 | Systematic Genetic Dissection of Human Erythropoiesis | 4 | 2025 |
| R01HL146500 | Next generation functional genomics of hematology traits | 4 | 2025 |
| U10CA180899 | Children's Oncology Group Statistics and Data Center | 4 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 3 | 2025 |
1 to 10 of 1,194Source NIH's project files
See all 1,194 nih grantsPapers1,870
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Uncovering molecular and functional dynamics of human hematopoietic stem cells during in vitro culture for cell therapy manufacturing. | Cytotherapy | 2026 | 42556173 | PubTator, text mining | PubMed |
| A synchronous counter-positive strategy via online CE-SELEX for high-efficiency aptamer selection. | J Chromatogr A | 2026 | 42176419 | PubTator, text mining | PubMed |
| The inhibitory effect of hepatic cancer energy metabolism on immune checkpoint therapy: perspectives from single-cell multi-omics analysis. | Front Immunol | 2026 | 42051493 | PubTator, text mining | PubMed |
| From Residency to Tissue Inflammatory Memory: HLF as a Transcriptional Gatekeeper of CD4 + Tissue-Resident Memory T Cells. | Respirology | 2026 | 42026931 | PubTator, text mining | PubMed |
| Advances in the diagnosis and classification of B-ALL: comparative insights from updated guidelines. | Blood Adv | 2026 | 41886641 | PubTator, text mining | PubMed |
| Transient SUMOylation inhibition in human pre-adipocytes stably imprints a transcriptional beiging fate. | Nucleic Acids Res | 2026 | 41854078 | PubTator, text mining | PubMed |
| Lactoferrin blocks orthopoxvirus entry via heparan sulphate and regulates host antiviral pathways. | Emerg Microbes Infect | 2026 | 41790953 | PubTator, text mining | PubMed |
| Modeling mitochondrial inheritance enables high-precision single-cell lineage tracing in humans. | bioRxiv | 2026 | 41726901 | PubTator, text mining | PubMed |
| A review of treatment strategies for elderly patients with Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia. | Transl Oncol | 2026 | 41690286 | PubTator, text mining | PubMed |
| Single cell atlas decodes the molecular dynamics of scar repair after human rotator cuff tear. | Bone Res | 2026 | 41644521 | PubTator, text mining | PubMed |
1 to 10 of 1,870
See all 1,870 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3131
GET https://conductscience.org/api/genes/v1/3131/patents?page=2