Gene · 3134
HLA-F: major histocompatibility complex, class I, F
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HLA-F: major histocompatibility complex, class I, F. Genes, record 3134. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3134
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P30511 | HLA class I histocompatibility antigen, alpha chain F | 346 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents49
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026222388 A1 | 2026-10-22 | 18 | P30511 | Espacenet |
| EP 4801948 A1 | 2026-09-09 | 47 | P30511 | Espacenet |
| JP 2026500670 A | 2026-01-08 | 18 | P30511 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6088 | P30511 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 327 | P30511 | Espacenet |
| EP 4641203 A2 | 2025-10-29 | 186 | P30511 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1972 | P30511 | Espacenet |
| KR 1020250127134 A | 2025-08-26 | 18 | P30511 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1972 | P30511 | Espacenet |
| JP 2025517967 A | 2025-06-12 | 186 | P30511 | Espacenet |
1 to 10 of 49
See all 49 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,180
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HLA-F papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| U01AI090905 | Insights Into Immune-Related Diseases Born from Population Genomics | 6 | 2025 |
| P30AI027757 | University of Washington/Fred Hutch Center for AIDS Research | 4 | 2025 |
| P01CA018029 | Adult Leukemia Research Center | 3 | 2025 |
| P30AI036214 | San Diego Center for AIDS Research (SD CFAR) | 3 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 3 | 2025 |
| T32AI007290 | Molecular and Cellular Immunobiology | 3 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 3 | 2025 |
| ZIABC010791 | Effects of genetic polymorphism in MHC, KIR, and related loci on human disease | 3 | 2025 |
1 to 10 of 1,180Source NIH's project files
See all 1,180 nih grantsPapers1,531
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cell Type-Resolved Causal Inference and Spatial Transcriptomic Integration Reveal Immune-Specific Genetic Drivers of Autoimmune and Malignant Thyroid Disease. | Int J Immunogenet | 2026 | 42734902 | PubTator, text mining | PubMed |
| Emerging therapeutic opportunities targeting nonclassical MHC-I molecules. | Trends Mol Med | 2026 | 42604821 | PubTator, text mining | PubMed |
| Genetic Diversity and Haplotype Architecture of Non-Classical HLA Class I Genes in the Japanese Population. | HLA | 2026 | 42576171 | PubTator, text mining | PubMed |
| Application of single-cell RNA sequencing in preeclampsia. | Front Glob Womens Health | 2026 | 42367612 | PubTator, text mining | PubMed |
| Expanded Allelic Diversity of Non-Classical HLA Class I and MIC Loci Identified Using Full-Gene Hybrid Capture-Based Next-Generation Sequencing. | HLA | 2026 | 42366455 | PubTator, text mining | PubMed |
| Type I Interferon Regulation of HLA-F Expression in Human Trophoblasts During Viral Infection. | Viruses | 2026 | 42357613 | PubTator, text mining | PubMed |
| Spatial Analysis Identifies Endothelial HLA-F as a Prognostic Marker in Antibody-mediated Rejection. | Transplantation | 2026 | 42302751 | PubTator, text mining | PubMed |
| Last Licensed Non-Classical Peptide Presenter HLA-F: Its Occurrence, Immunoediting Significance, and Possible Therapeutic Implications in Renal Cell Carcinoma. | Int J Mol Sci | 2026 | 42278594 | PubTator, text mining | PubMed |
| PSD3 links autophagic flux to MHC-I-associated immune modulation in esophageal squamous cell carcinoma. | Apoptosis | 2026 | 42149295 | PubTator, text mining | PubMed |
| Nonclassical MHC-I Molecules: Emerging Therapeutic Targets in Next-Generation Immunotherapy. | MedComm (2020) | 2026 | 42027260 | PubTator, text mining | PubMed |
1 to 10 of 1,531
See all 1,531 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3134
GET https://conductscience.org/api/genes/v1/3134/patents?page=2