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Gene · 3159

HMGA1: high mobility group AT-hook 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HMGA1: high mobility group AT-hook 1. Genes, record 3159. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3159

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Gene

Symbol
HMGA1
HGNC
Name
high mobility group AT-hook 1
HGNC
NCBI Gene ID
3159
NCBI Gene
HGNC ID
HGNC:5010
HGNC
Ensembl
ENSG00000137309
NCBI Gene
Aliases
HMG-R, HMGA1A, HMGIY
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P17096High mobility group protein HMG-I/HMG-Y1075Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449063P17096Espacenet
JP 2026004568 A2026-01-1449066P17096Espacenet
JP 2026004568 A2026-01-1449070P17096Espacenet
EP 4650780 A22025-11-194544P17096Espacenet
EP 4641202 A22025-10-294830P17096Espacenet
JP 2025147176 A2025-10-0615097P17096Espacenet
EP 4574155 A12025-06-253P17096Espacenet
JP 2025517970 A2025-06-124544P17096Espacenet
JP 2025028160 A2025-02-2815097P17096Espacenet
KR 1020250017231 A2025-02-044830P17096Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,135

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHMGA1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant142025
P30CA016672Cancer Center Support Grant112025
P30CA006973Regional Oncology Research Center82025
P30CA010815Consolidated Basic Cancer Research Program62025
P30CA068485Cancer Center Support Grant52025
T32CA009171Training Program in Basic Cancer Research52025
P30CA016058Cancer Center Support Grant42025
ZIAHG000024Genetic analysis of type II diabetes42025
P20GM109036Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases32025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant32025

1 to 10 of 2,135Source NIH's project files

See all 2,135 nih grants

Papers3,810

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Heat-preconditioned MSC-derived exosomal miR‑486‑5p reverses doxorubicin resistance in breast cancer.Nanomedicine (Lond)202642821374PubTator, text miningPubMed
ERRATUM to: Intracellular FGF1 promotes invasion and migration in thyroid carcinoma via HMGA1 independent of FGF receptors.Endocr Connect202642743414PubTator, text miningPubMed
Pan-cancer characterization of HMGA1 reveals its oncogenic role in tumor microenvironment and stemness: functional validation in pancreatic cancer migration and invasion.Transl Cancer Res202642724846PubTator, text miningPubMed
Targeting MYCN Degradation by HLB-0532259 Induces Senescence in Retinoblastoma.Invest Ophthalmol Vis Sci202642615797PubTator, text miningPubMed
Identifying Epithelial-Cell Progression Signatures (ECPSs) from Multi-Resolution Multi-Omics Data for Translational Clinical Applications in Lung Adenocarcinoma.Int J Mol Sci202642589474PubTator, text miningPubMed
HMGA1 is associated with unfavorable outcome and accelerates the aggressiveness of cholangiocarcinoma.SAGE Open Med202642558860PubTator, text miningPubMed
A five-gene TAM and MYCN signature predicts prognosis and identifies MTHFD2 as a therapeutic target in neuroblastoma.Discov Oncol202642550464PubTator, text miningPubMed
Tumor-associated macrophages and lineage plasticity in prostate cancer: from established myeloid programs to emerging spatial hypotheses.Front Immunol202642516385PubTator, text miningPubMed
Differentially Methylated Regions in Human Rhombic Lip Compartments Are Enriched in Putative Active Enhancers, Human Accelerated Regions, and Medulloblastoma Copy Number Aberrations.Cerebellum202642479105PubTator, text miningPubMed
Biomarkers of the tumor microenvironment for prognostication of recurrence in glioma and targeting stemness using an adjuvant.Discov Oncol202642471533PubTator, text miningPubMed

1 to 10 of 3,810

See all 3,810 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3159

GET https://conductscience.org/api/genes/v1/3159/patents?page=2