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HMOX1: heme oxygenase 1

1 protein, 101 patents, 0 drugs, 0 trials, 8,668 NIH grants and 35,166 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHMOX1HGNC
Nameheme oxygenase 1HGNC
NCBI Gene ID3162NCBI Gene
HGNC IDHGNC:5013HGNC
EnsemblENSG00000100292NCBI Gene
AliasesHMOX1D, HO-1, HSP32, bK286B10NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P09601Heme oxygenase 128826Ensembl, GeneID, HGNCUniProt

Patents 101

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19307P09601Espacenet
EP 4641202 A22025-10-2912P09601Espacenet
JP 2025529142 A2025-09-041976P09601Espacenet
US 12371689 B22025-07-291976P09601Espacenet
JP 2025517970 A2025-06-12307P09601Espacenet
US 12247257 B22025-03-113P09601Espacenet
KR 1020250020708 A2025-02-111P09601Espacenet
KR 1020250017231 A2025-02-0412P09601Espacenet
JP 2024167327 A2024-12-031P09601Espacenet
JP 2024123008 A2024-09-106420P09601Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8668

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30ES006694Southwest Environmental Health Sciences Center822,025NIH's project files
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)692,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant422,025NIH's project files
P30CA016672Cancer Center Support Grant362,025NIH's project files
P30ES001247Environmental Agents as Modulators of Disease Processes342,025NIH's project files
T32ES007091Training in Environmental Toxicology of Human Disease342,025NIH's project files
R01DK062357HuR/HIF – SIRT1 Signaling Axis in Liver Transplant Rejuvenation292,025NIH's project files
R01ES004738Activated Macrophages and Ozone Toxicity272,025NIH's project files
R01ES007331Mechanisms of Methylmercury Induced Neuronal Toxicity232,025NIH's project files
R01ES010563Mechanisms of Manganese Neurotoxicity202,025NIH's project files

Papers 35166

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827322PubTator, text miningPubMed
42825897PubTator, text miningPubMed
42821452PubTator, text miningPubMed
42821430PubTator, text miningPubMed
42819011PubTator, text miningPubMed
42818246PubTator, text miningPubMed
42815280PubTator, text miningPubMed
42810523PubTator, text miningPubMed
42808252PubTator, text miningPubMed
42803694PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license