Gene · 3192
HNRNPU: heterogeneous nuclear ribonucleoprotein U
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HNRNPU: heterogeneous nuclear ribonucleoprotein U. Genes, record 3192. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3192
On this page
Gene
- Aliases
- C1orf199, DEE54, EIEE54, FLJ30202, FLJ37978, GRIP120, HNRNPU-AS1, HNRPU, NCRNA00201, SAF-A, SAFA, U21.1, hnRNP U, pp120
- NCBI Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q00839 | Heterogeneous nuclear ribonucleoprotein U | 825 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents13
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 19230 | Q00839 | Espacenet |
| WO 2025187175 A | 2025-09-11 | 10 | Q00839 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19230 | Q00839 | Espacenet |
| WO 2024204642 A | 2024-10-03 | 1 | Q00839 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 5073 | Q00839 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 38142 | Q00839 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 141113 | Q00839 | Espacenet |
| US 10463751 B2 | 2019-11-05 | 5073 | Q00839 | Espacenet |
| JP 2018023373 A | 2018-02-15 | 27800 | Q00839 | Espacenet |
| US 9572897 B2 | 2017-02-21 | 5073 | Q00839 | Espacenet |
1 to 10 of 13
See all 13 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,645
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HNRNPU papers | Newest fiscal year |
|---|---|---|---|
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 15 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| R35GM122597 | RNA and Genomic Junk in Fundamental Chromosome Architecture and Regulation | 6 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 5 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 5 | 2025 |
| T32CA009110 | Training in Areas Fundamental to Cancer Research | 5 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 4 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
1 to 10 of 1,645Source NIH's project files
See all 1,645 nih grantsPapers2,251
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SAF-A/HNRNPU regulates euchromatin dynamics and is required for nuclear envelope integrity. | bioRxiv | 2026 | 42818705 | PubTator, text mining | PubMed |
| Disrupted PQBP1-HNRNPU-LINE-1 axis underlies aberrant neurodevelopment in renpenning syndrome. | Mol Psychiatry | 2026 | 42786260 | PubTator, text mining | PubMed |
| Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat. | J Clin Lab Anal | 2026 | 42605264 | PubTator, text mining | PubMed |
| [The Clinical Significance and in vitro Experimental Study of hnRNP U in Multiple Myeloma]. | Zhongguo Shi Yan Xue Ye Xue Za Zhi | 2026 | 42544663 | PubTator, text mining | PubMed |
| Global Phosphoproteome Analysis Identifies CLK4 Co-Regulatory Pathways Driving Tumor-Specific Dysregulation. | OMICS | 2026 | 42484065 | PubTator, text mining | PubMed |
| Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation. | Science | 2026 | 42348677 | PubTator, text mining | PubMed |
| Clustered monoallelic mosaicism in twins suggests previously unrecognized path of mutagenesis. | HGG Adv | 2026 | 42332879 | PubTator, text mining | PubMed |
| The SAF-A/HNRNPU ATPase and RGG domains are important for XIST RNA localization, nuclear dynamics, RNA splicing, and cell proliferation. | Mol Biol Cell | 2026 | 42234592 | PubTator, text mining | PubMed |
| HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism. | Adv Sci (Weinh) | 2026 | 42201673 | PubTator, text mining | PubMed |
| Dysregulated competitive splicing between circular and linear RNAs characterizes hepatocellular carcinoma tumorigenesis and recurrence. | Biol Direct | 2026 | 42135846 | PubTator, text mining | PubMed |
1 to 10 of 2,251
See all 2,251 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3192
GET https://conductscience.org/api/genes/v1/3192/patents