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Gene · 3192

HNRNPU: heterogeneous nuclear ribonucleoprotein U

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HNRNPU: heterogeneous nuclear ribonucleoprotein U. Genes, record 3192. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3192

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Gene

Symbol
HNRNPU
HGNC
Name
heterogeneous nuclear ribonucleoprotein U
HGNC
NCBI Gene ID
3192
NCBI Gene
HGNC ID
HGNC:5048
HGNC
Ensembl
ENSG00000153187
NCBI Gene
Aliases
C1orf199, DEE54, EIEE54, FLJ30202, FLJ37978, GRIP120, HNRNPU-AS1, HNRPU, NCRNA00201, SAF-A, SAFA, U21.1, hnRNP U, pp120
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q00839Heterogeneous nuclear ribonucleoprotein U8250Ensembl, GeneID, HGNC

Source UniProt

Patents13

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1919230Q00839Espacenet
WO 2025187175 A2025-09-1110Q00839Espacenet
JP 2025517970 A2025-06-1219230Q00839Espacenet
WO 2024204642 A2024-10-031Q00839Espacenet
US 11564998 B22023-01-315073Q00839Espacenet
US 11446398 B22022-09-2038142Q00839Espacenet
JP 2022524081 A2022-04-27141113Q00839Espacenet
US 10463751 B22019-11-055073Q00839Espacenet
JP 2018023373 A2018-02-1527800Q00839Espacenet
US 9572897 B22017-02-215073Q00839Espacenet

1 to 10 of 13

See all 13 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,645

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHNRNPU papersNewest fiscal year
P01CA092584Structural Cell Biology of DNA Repair Machines152025
P30CA008748Cancer Center Support Grant82025
R35GM122597RNA and Genomic Junk in Fundamental Chromosome Architecture and Regulation62025
P30DK020572Michigan Diabetes Research Center (MDRC)52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025
T32CA009110Training in Areas Fundamental to Cancer Research52025
P30CA006927Comprehensive Cancer Center Program at Fox Chase42025
P30CA016058Cancer Center Support Grant42025
P30CA016672Cancer Center Support Grant42025
P30CA021765Cancer Center Support Grant (CCSG)42025

1 to 10 of 1,645Source NIH's project files

See all 1,645 nih grants

Papers2,251

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SAF-A/HNRNPU regulates euchromatin dynamics and is required for nuclear envelope integrity.bioRxiv202642818705PubTator, text miningPubMed
Disrupted PQBP1-HNRNPU-LINE-1 axis underlies aberrant neurodevelopment in renpenning syndrome.Mol Psychiatry202642786260PubTator, text miningPubMed
Clinical and Cytogenomic Characterization of Three Patients With Distal 1q43q44 Deletion: Twin Sisters With a de novo Deletion and a Patient With der(1)t(1;21)(q43;q22.3)mat.J Clin Lab Anal202642605264PubTator, text miningPubMed
[The Clinical Significance and in vitro Experimental Study of hnRNP U in Multiple Myeloma].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642544663PubTator, text miningPubMed
Global Phosphoproteome Analysis Identifies CLK4 Co-Regulatory Pathways Driving Tumor-Specific Dysregulation.OMICS202642484065PubTator, text miningPubMed
Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation.Science202642348677PubTator, text miningPubMed
Clustered monoallelic mosaicism in twins suggests previously unrecognized path of mutagenesis.HGG Adv202642332879PubTator, text miningPubMed
The SAF-A/HNRNPU ATPase and RGG domains are important for XIST RNA localization, nuclear dynamics, RNA splicing, and cell proliferation.Mol Biol Cell202642234592PubTator, text miningPubMed
HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism.Adv Sci (Weinh)202642201673PubTator, text miningPubMed
Dysregulated competitive splicing between circular and linear RNAs characterizes hepatocellular carcinoma tumorigenesis and recurrence.Biol Direct202642135846PubTator, text miningPubMed

1 to 10 of 2,251

See all 2,251 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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