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Gene · 325

APCS: amyloid P component, serum

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. APCS: amyloid P component, serum. Genes, record 325. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/325

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
APCS
HGNC
Name
amyloid P component, serum
HGNC
NCBI Gene ID
325
NCBI Gene
HGNC ID
HGNC:584
HGNC
Ensembl
ENSG00000132703
NCBI Gene
Aliases
HEL-S-92n, MGC88159, PTX2, SAP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P02743Serum amyloid P-component22313Ensembl, GeneID, HGNC

Source UniProt

Patents80

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026000906 A2026-01-06122P02743Espacenet
WO 2025262255 A12025-12-2616P02743Espacenet
EP 4650780 A22025-11-191531P02743Espacenet
JP 2025169942 A2025-11-14810P02743Espacenet
EP 4641201 A22025-10-291144P02743Espacenet
JP 2025147176 A2025-10-06914P02743Espacenet
JP 2025529142 A2025-09-045497P02743Espacenet
US 12371689 B22025-07-295497P02743Espacenet
JP 2025517969 A2025-06-121144P02743Espacenet
JP 2025517970 A2025-06-121531P02743Espacenet

1 to 10 of 80

See all 80 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DEZAMIZUMABCHEMBL4297966Serum amyloid P-component inhibitorINHIBITORChEMBL
MIRIDESAPCHEMBL25263Serum amyloid P-component cross-linking agentCROSS-LINKING AGENTChEMBL

Trials4

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03044353MIRIDESAPPHASE22019-10-16ClinicalTrials.gov
NCT02425241MIRIDESAPPHASE1/PHASE2ClinicalTrials.gov
NCT01777243MIRIDESAPPHASE1ClinicalTrials.gov
NCT01777243DEZAMIZUMABPHASE1ClinicalTrials.gov

NIH grants1,621

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant172025
P30CA008748Cancer Center Support Grant112025
UL1TR001863Yale Clinical and Translational Science Award62025
P30CA015704Cancer Center Support Grant52025
P30CA016058Cancer Center Support Grant52025
P20GM103475Advancing Competitive Biomedical Research in Puerto Rico42025
P30AI027763UCSF-Bay Area Center for AIDS Research42025
U54MD007600Center for Collaborative Research in Health Disparities42025
P30CA036727Buffett Cancer Center Support Grant32025
P30DK017047Diabetes Research Center32025

1 to 10 of 1,621Source NIH's project files

See all 1,621 nih grants

Papers4,193

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42803180PubTator, text miningPubMed
42668852PubTator, text miningPubMed
42586276PubTator, text miningPubMed
42575345PubTator, text miningPubMed
42521538PubTator, text miningPubMed
42469859PubTator, text miningPubMed
42115887PubTator, text miningPubMed
42112480PubTator, text miningPubMed
41892354PubTator, text miningPubMed
41835451PubTator, text miningPubMed

1 to 10 of 4,193

See all 4,193 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/325

GET https://conductscience.org/api/genes/v1/325/patents?page=2