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AIRE: autoimmune regulator
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Gene · 326

Papers2,741

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,741

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TitleJournalYearPMIDFound bySource
Aire is a cell-intrinsic regulator of natural IgM-secreting cells.Immunity202642815461PubTator, text miningPubMed
Vitamin D signaling in thymic development and longevity.Front Nutr202642812403PubTator, text miningPubMed
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED): Epidemiology, Pathogenesis, Clinical Manifestations, Diagnosis, and Management.Endocr Metab Immune Disord Drug Targets202642786839PubTator, text miningPubMed
Genetic Heterogeneity of Inborn Errors of Immunity Revealed by Whole-Genome Sequencing: Insights from a Russian Patient Cohort.Int J Mol Sci202642737820PubTator, text miningPubMed
NETs mediate neuropathic pain in PSS-PN by participating in inflammatory injury to the vasa nervorum.Clin Rheumatol202642696213PubTator, text miningPubMed
Cancer Immunotherapy Using AIRE Conditioning of the Tumor Epitopeome.Cancer Immunol Res202642644627PubTator, text miningPubMed
Genetic context shapes interpretation of AIRE and Notch4 in alopecia areata.JID Innov202642633099PubTator, text miningPubMed
Thymic selection of the T cell receptor repertoire is biased toward autoimmunity in females.Elife202642623268PubTator, text miningPubMed
Multi-omics-guided targeting of the CD14-NF-κB axis with PGA1-loaded liposomes restores CD14hi TSPCs function and promotes tendon-bone healing in diabetes.Mater Today Bio202642603967PubTator, text miningPubMed
Alopecia Areata Associated With a Dominant AIRE Variant.J Dermatol202642587409PubTator, text miningPubMed
Systematic and proactive evaluation of AIRE missense variant effects.Am J Hum Genet202642561935PubTator, text miningPubMed
Clinical spectrum and long-term follow-up of non-surgical hypoparathyroidism with novel AIRE and GATA3 variants from India.Endocrine202642560401PubTator, text miningPubMed
Clinical, genetic, and immunologic features of APS-1 patients from the Middle East, and a review of the literature.J Hum Immun202642549229PubTator, text miningPubMed
AIRE transcriptional condensates in central tolerance: a multiscale mechanistic perspective.Front Immunol202642528816PubTator, text miningPubMed
Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance.Immunology202642493359PubTator, text miningPubMed
Approach to the patient with APS-1/APECED.J Clin Endocrinol Metab202642460781PubTator, text miningPubMed
Preliminary Evidence for Autoimmune Regulator Occupancy at Promoter Regions of Known Autoantigens in Human Peripheral Lymphocytes Obtained by Chromatin Immunoprecipitation Assay.Int J Mol Sci202642450080PubTator, text miningPubMed
The autoimmune regulator (AIRE) is a target of the E3-Ubiquitin ligase Seven-in-absentia homolog 1 (SIAH1).Apoptosis202642449076PubTator, text miningPubMed
Could molecular variations be predictive in right and left colon cancer in different gender and age groups?PLoS One202642430378PubTator, text miningPubMed
Clinical rationale for thymic restoration in adult immunosenescence.Immun Ageing202642415124PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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