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HRAS: HRas proto-oncogene, GTPase

1 protein, 404 patents, 1 drug, 0 trials, 8,831 NIH grants and 19,900 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHRASHGNC
NameHRas proto-oncogene, GTPaseHGNC
NCBI Gene ID3265NCBI Gene
HGNC IDHGNC:5173HGNC
EnsemblENSG00000174775NCBI Gene
AliasesC-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, RASH1, p21rasNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01112GTPase HRas189246Ensembl, GeneID, HGNCUniProt

Patents 404

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4829006 A12026-10-2870P01112Espacenet
EP 4825362 A12026-10-2145P01112Espacenet
EP 4805358 A12026-09-167P01112Espacenet
EP 4803075 A12026-09-0945P01112Espacenet
EP 4780964 A12026-07-2961P01112Espacenet
EP 4777629 A12026-07-2267P01112Espacenet
EP 4762183 A12026-06-2433P01112Espacenet
EP 4754118 A12026-06-107P01112Espacenet
JP 2026094314 A2026-06-0971P01112Espacenet
JP 2026086799 A2026-05-262P01112Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
SALIRASIBCHEMBL23293RAS inhibitorINHIBITORChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 8831

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2522,025NIH's project files
P30CA016672Cancer Center Support Grant2082,025NIH's project files
P30CA006973Regional Oncology Research Center392,025NIH's project files
P50CA097190Head and Neck Cancer SPORE352,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant342,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award342,025NIH's project files
ZIABC010440Protein Structure, Stability, and Amyloid Formation342,025NIH's project files
ZIABC010441Biomolecular Recognition and Binding Mechanisms342,025NIH's project files
P30CA068485Cancer Center Support Grant312,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase302,025NIH's project files

Papers 19900

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827359PubTator, text miningPubMed
42820254PubTator, text miningPubMed
42812597PubTator, text miningPubMed
42782272PubTator, text miningPubMed
42777841PubTator, text miningPubMed
42773328PubTator, text miningPubMed
42758366PubTator, text miningPubMed
42748471PubTator, text miningPubMed
42747807PubTator, text miningPubMed
42730891PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license