Gene · 327
APEH: acylaminoacyl-peptide hydrolase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. APEH: acylaminoacyl-peptide hydrolase. Genes, record 327. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/327
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P13798 | Acylamino-acid-releasing enzyme | 732 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents15
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 54887 | P13798 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3724 | P13798 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3724 | P13798 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 1798 | P13798 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 1798 | P13798 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 104769 | P13798 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 628 | P13798 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 235322 | P13798 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 235322 | P13798 | Espacenet |
| JP 2015516143 A | 2015-06-08 | 235322 | P13798 | Espacenet |
1 to 10 of 15
See all 15 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants716
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | APEH papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 4 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 3 | 2025 |
| R01GM095970 | Protein-protein interactions in natural product biosynthesis | 3 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 2 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 2 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 2 | 2025 |
| R01AI171514 | Structure-based microbially targeted prodrugs | 2 | 2025 |
1 to 10 of 716Source NIH's project files
See all 716 nih grantsPapers1,530
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| AI-Decoded Multicatalytic Activities Nanozyme Platform: Integrated Identification and Quantification of Multiplexed Pesticide Residues. | J Agric Food Chem | 2026 | 42616408 | PubTator, text mining | PubMed |
| Recombinant Nus-organophosphorus hydrolase (OPH) immobilized carbon quantum dot (CQD) loaded thin films for efficient detection of OP compounds in environmental samples. | Analyst | 2026 | 42615109 | PubTator, text mining | PubMed |
Synergistically Functioning Cobalt and Zinc Active Centers from the Pyrolysis of Their Bimetallic ZIFs Exhibiting Orders-of-Magnitude Higher Organophosphorus Hydrolase-Mimicking Activity than Either One Alone. | ACS Omega | 2026 | 42598353 | PubTator, text mining | PubMed |
| A Brain-Targeted Organophosphorus Hydrolase Fusion Protein Mediated by Angiopep-2 Neutralizes Central Organophosphates and Alleviates Neurotoxicity. | Int J Nanomedicine | 2026 | 42368404 | PubTator, text mining | PubMed |
| Protein Abundance of Hydrolytic Drug Metabolizing Enzymes in Different Tissues and across Species. | J Med Chem | 2026 | 42342236 | PubTator, text mining | PubMed |
| Microbial degradation of organophosphorus pesticides: mechanisms, environmental impacts, and future perspectives. | World J Microbiol Biotechnol | 2026 | 42240700 | PubTator, text mining | PubMed |
| Transfer RNA-derived small RNA-Gly activates the ACPH/GRHL1 axis to facilitate liver cell regeneration in acute-on chronic liver failure. | Sci China Life Sci | 2026 | 42207451 | PubTator, text mining | PubMed |
| Ecological and genomic insights into Bacillus altitudinis as a potential indicator of resistance genes in soil antimicrobial resistance pools. | Environ Sci Pollut Res Int | 2026 | 42113401 | PubTator, text mining | PubMed |
| Bioremediation of organophosphorus compounds using highly stable packed bed microreactor developed with OPH (organophosphorus hydrolase) coated nanofiber. | Environ Technol | 2026 | 41946508 | PubTator, text mining | PubMed |
| PEGylated organophosphorus hydrolase combined with butyrylcholinesterase: dual-enzyme synergistic biocatalysis for acute organophosphate poisoning. | Bioorg Chem | 2026 | 41946000 | PubTator, text mining | PubMed |
1 to 10 of 1,530
See all 1,530 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/327
GET https://conductscience.org/api/genes/v1/327/patents