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Gene · 3273

HRG: histidine rich glycoprotein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HRG: histidine rich glycoprotein. Genes, record 3273. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3273

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Gene

Symbol
HRG
HGNC
Name
histidine rich glycoprotein
HGNC
NCBI Gene ID
3273
NCBI Gene
HGNC ID
HGNC:5181
HGNC
Ensembl
ENSG00000113905
NCBI Gene
Aliases
HPRG, HRGP, THPH11
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P04196Histidine-rich glycoprotein5250Ensembl, GeneID, HGNC

Source UniProt

Patents97

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12534732 B22026-01-27910P04196Espacenet
JP 2026012378 A2026-01-23910P04196Espacenet
JP 2026004568 A2026-01-1449133P04196Espacenet
US 12516329 B22026-01-06910P04196Espacenet
EP 4670792 A22025-12-31910P04196Espacenet
EP 4650780 A22025-11-19821P04196Espacenet
KR 1020250160362 A2025-11-12910P04196Espacenet
EP 4641201 A22025-10-29583P04196Espacenet
JP 2025147176 A2025-10-066566P04196Espacenet
JP 2025529142 A2025-09-046610P04196Espacenet

1 to 10 of 97

See all 97 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants732

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHRG papersNewest fiscal year
P30CA008748Cancer Center Support Grant32025
P30CA015704Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
R35GM142695Statistical and Machine Learning Methods to Address Biomedical Challenges for Integrating Multi-view Data32025
T32GM008315Mechanisms of Trauma-Induced Coagulopathy32025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer22025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)22025
P30CA016520Abramson Cancer Center Support Grant22025
P30CA068485Cancer Center Support Grant22025

1 to 10 of 732Source NIH's project files

See all 732 nih grants

Papers1,508

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Pilot Study Beyond Ovarian Reserve: How AMH Levels Shape the Proteomic and Metabolic Landscape of the Follicle.Reprod Med Biol202642780541PubTator, text miningPubMed
Hereditary thrombophilia due to a novel histidine-rich glycoprotein mutation leading to deferral of kidney transplantation: a case report.Blood Coagul Fibrinolysis202642712169PubTator, text miningPubMed
Ligand-dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry.FEBS Lett202642629963PubTator, text miningPubMed
Exploratory proteomic and metabolomic profiling of pleural effusions identifies histone H4 and alanine as promising complementary markers for pleural tuberculosis.Tuberculosis (Edinb)202642623998PubTator, text miningPubMed
Genomic Evidence Links Inflammation to Residual Pulmonary Vascular Obstruction and Risk of Pulmonary Embolism Recurrence.medRxiv202642465927PubTator, text miningPubMed
SPP1+ Macrophages Promote Immunosuppression in Post-TACE Hepatocellular Carcinoma Involving Lactate-Induced Lactylation and Potential SPP1-CD44 Signaling.J Hepatocell Carcinoma202642438784PubTator, text miningPubMed
Establishment of a versatile histidine-rich glycoprotein (HRG) measurement methodology bearing a highly compatible design for patients with sepsis in daily clinical practice.J Immunol Methods202642425266PubTator, text miningPubMed
An Insight Into a Potential Antithrombin-Independent Mechanism of Inadequate Heparin Response in Neonates and Infants Undergoing Pediatric Cardiac Surgery: An Exploratory Study.J Cardiothorac Vasc Anesth202642386483PubTator, text miningPubMed
Predictive biomarkers of COVID-19 impact in renal transplant patients: an exploratory proteomic and cytokine analysis.Front Immunol202642367818PubTator, text miningPubMed
Histidine-rich glycoprotein modulates platelet adhesion and aggregation by binding to GPIbα and GPIIb/IIIa.Blood202642237632PubTator, text miningPubMed

1 to 10 of 1,508

See all 1,508 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3273

GET https://conductscience.org/api/genes/v1/3273/patents?page=2