Gene · 3292
HSD17B1: hydroxysteroid 17-beta dehydrogenase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HSD17B1: hydroxysteroid 17-beta dehydrogenase 1. Genes, record 3292. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3292
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P14061 | 17-beta-hydroxysteroid dehydrogenase type 1 | 328 | 28 | Ensembl, GeneID, HGNC |
Source UniProt
Patents15
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 49544 | P14061 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 49545 | P14061 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 39297 | P14061 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 142268 | P14061 | Espacenet |
| KR 1020210125456 A | 2021-10-18 | 12 | P14061 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 5187 | P14061 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 229979 | P14061 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 229980 | P14061 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 229979 | P14061 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 229980 | P14061 | Espacenet |
1 to 10 of 15
See all 15 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,127
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HSD17B1 papers | Newest fiscal year |
|---|---|---|---|
| P30ES013508 | Center of Excellence in Environmental Toxicology | 19 | 2025 |
| T32ES007326 | Interdisciplinary Research Training Program in Environmental Health and Toxicology | 8 | 2025 |
| R01CA172382 | Elucidating a novel molecular biomarker for castration-resistant prostate cancer | 6 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 5 | 2025 |
| T32DK007314 | Diabetes, Endocrine, and Metabolism | 4 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| P30ES005022 | Rutgers Center for Environmental Exposure and Disease (CEED) | 3 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 3 | 2025 |
1 to 10 of 1,127Source NIH's project files
See all 1,127 nih grantsPapers2,290
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Dietary vitamin C improves reproductive performance by increasing antioxidant capacity, steroid hormone concentration and expression of genes involved in steroid hormone synthesis in Yangzhou geese. | Br Poult Sci | 2026 | 42813264 | PubTator, text mining | PubMed |
| Molecular Mechanisms of Endocrine-Disrupting Chemicals and Emerging-Pollutant Toxicity in Human Reproduction: From Xenobiotic Exposure to Fertility Impairment and Reproductive Carcinogenesis. | Int J Mol Sci | 2026 | 42737662 | PubTator, text mining | PubMed |
A Phase 2a/b, Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Study to Evaluate the Efficacy and Safety of Linustedastat (OG-6219) in Women with Moderate to Severe Endometriosis-Related Pain. | Int J Womens Health | 2026 | 42733850 | PubTator, text mining | PubMed |
| Association of organophosphate flame retardant exposure with female infertility: Cross-sectional and mechanistic evidence. | Ecotoxicol Environ Saf | 2026 | 42710202 | PubTator, text mining | PubMed |
| Saliva-based RT-LAMP assays support heat shock protein 70 as a promising transcript marker for estrus identification in buffaloes. | Trop Anim Health Prod | 2026 | 42709327 | PubTator, text mining | PubMed |
| Serum Peptidomic Analysis in a Comparative Study of the Efficacy of Benjakul Remedy Versus Loratadine in Allergic Rhinitis Patients. | Int J Mol Sci | 2026 | 42653391 | PubTator, text mining | PubMed |
| Design, synthesis, and preliminary antiproliferative evaluation of azetidine-functionalized pyrrolo[2,3-d]pyrimidines with integrated computational studies. | J Biomol Struct Dyn | 2026 | 42627359 | PubTator, text mining | PubMed |
| Effects of PFOS and its substitute PFHxS on steroid hormone secretion, uptake, and transport in BeWo cells. | Ecotoxicol Environ Saf | 2026 | 42561515 | PubTator, text mining | PubMed |
| Identification of genes differentially expressed in granulosa cells from women with high vs. low ovarian responsiveness. | Front Reprod Health | 2026 | 42358728 | PubTator, text mining | PubMed |
| Targeting Steroid-Metabolizing Enzymes with 15β-Substituted Estrone Analogues: Dual Discovery of AKR1C2/17β-HSD1 Inhibitors and a Fluorescent 17β-HSD1 Ligand. | Cancers (Basel) | 2026 | 42352425 | PubTator, text mining | PubMed |
1 to 10 of 2,290
See all 2,290 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3292
GET https://conductscience.org/api/genes/v1/3292/patents