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HSF1: heat shock transcription factor 1

1 protein, 78 patents, 0 drugs, 0 trials, 3,408 NIH grants and 6,320 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHSF1HGNC
Nameheat shock transcription factor 1HGNC
NCBI Gene ID3297NCBI Gene
HGNC IDHGNC:5224HGNC
EnsemblENSG00000185122NCBI Gene
AliasesHSTF1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q00613Heat shock factor protein 15298Ensembl, GeneID, HGNCUniProt

Patents 78

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026094314 A2026-06-0951Q00613Espacenet
JP 2026021360 A2026-02-10142Q00613Espacenet
JP 2026004568 A2026-01-1448823Q00613Espacenet
EP 4650780 A22025-11-1915428Q00613Espacenet
JP 2025147176 A2025-10-0615151Q00613Espacenet
JP 2025517970 A2025-06-1215428Q00613Espacenet
JP 2025041709 A2025-03-2669Q00613Espacenet
JP 2025028160 A2025-02-2815151Q00613Espacenet
JP 2025023947 A2025-02-1951Q00613Espacenet
JP 2025024092 A2025-02-19142Q00613Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3408

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P40OD010440Caenorhabditis Genetics Center412,025NIH's project files
P30CA008748Cancer Center Support Grant242,025NIH's project files
ZIASC010074HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction202,025NIH's project files
P30CA016672Cancer Center Support Grant192,025NIH's project files
R01CA062130Role of heat shock transcription factor HSF1 in tumorigenesis192,025NIH's project files
ZIABC011032Post-translational modifications of Hsp90122,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant112,025NIH's project files
P30CA034196Cancer Center Support (CORE) Grant102,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center102,025NIH's project files
R01NS059690Molecular Chaperones and Small Molecules102,025NIH's project files

Papers 6320

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817631PubTator, text miningPubMed
42805119PubTator, text miningPubMed
42764983PubTator, text miningPubMed
42758435PubTator, text miningPubMed
42738916PubTator, text miningPubMed
42704713PubTator, text miningPubMed
42674818PubTator, text miningPubMed
42656891PubTator, text miningPubMed
42632208PubTator, text miningPubMed
42632150PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license