ConductScience.org, home

Library / Genes

HSPA1A: heat shock protein family A (Hsp70) member 1A

2 proteins, 670 patents, 1 drug, 3 trials, 3,442 NIH grants and 6,532 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHSPA1AHGNC
Nameheat shock protein family A (Hsp70) member 1AHGNC
NCBI Gene ID3303NCBI Gene
HGNC IDHGNC:5232HGNC
EnsemblENSG00000204389NCBI Gene
AliasesHEL-S-103, HSP70, HSP70-1, HSP70-1A, HSP70-2, HSP70.1, HSP70.2, HSP70I, HSP72, HSPA1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 2

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P0DMV8Heat shock 70 kDa protein 1A64175Ensembl, GeneID, HGNCUniProt
P0DMV9Heat shock 70 kDa protein 1B6415Ensembl, GeneIDUniProt

Patents 670

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4822355 A22026-10-141P0DMV8Espacenet
EP 4822355 A22026-10-141P0DMV9Espacenet
EP 4822355 A22026-10-144P0DMV8Espacenet
EP 4822355 A22026-10-144P0DMV9Espacenet
JP 2026086489 A2026-05-2611P0DMV8Espacenet
JP 2026086489 A2026-05-2611P0DMV9Espacenet
JP 2026004568 A2026-01-1448739P0DMV8Espacenet
JP 2026004568 A2026-01-1448739P0DMV9Espacenet
JP 2026004568 A2026-01-1448744P0DMV8Espacenet
JP 2026004568 A2026-01-1448744P0DMV9Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CD24FCCHEMBL4297717Heat shock 70 kDa protein 1A/1B inhibitorINHIBITORChEMBL

Trials 3

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04317040CD24FCPHASE32021-10-15ClinicalTrials.gov
NCT04060407CD24FCPHASE1/PHASE2ClinicalTrials.gov
NCT03960541CD24FCPHASE22022-06-08ClinicalTrials.gov

NIH grants 3442

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01NS059690Molecular Chaperones and Small Molecules412,025NIH's project files
P30CA008748Cancer Center Support Grant252,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center232,025NIH's project files
P30CA016672Cancer Center Support Grant192,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant192,025NIH's project files
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)112,025NIH's project files
T32ES007091Training in Environmental Toxicology of Human Disease112,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant92,025NIH's project files
R01NS073899The hsp90 Cochaperone FKBP51 Regulates tau Structure and Function92,025NIH's project files
R01GM058460Chromatin Domain Structure and Function82,025NIH's project files

Papers 6532

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42802211PubTator, text miningPubMed
42790136PubTator, text miningPubMed
42786271PubTator, text miningPubMed
42767388PubTator, text miningPubMed
42759513PubTator, text miningPubMed
42759487PubTator, text miningPubMed
42731467PubTator, text miningPubMed
42729150PubTator, text miningPubMed
42728740PubTator, text miningPubMed
42679909PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license