Gene · 3304
HSPA1B: heat shock protein family A (Hsp70) member 1B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HSPA1B: heat shock protein family A (Hsp70) member 1B. Genes, record 3304. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3304
On this page
Gene
Proteins2
Reviewed human proteins whose Swiss-Prot entry states the gene.
Patents670
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4822355 A2 | 2026-10-14 | 1 | P0DMV8 | Espacenet |
| EP 4822355 A2 | 2026-10-14 | 1 | P0DMV9 | Espacenet |
| EP 4822355 A2 | 2026-10-14 | 4 | P0DMV8 | Espacenet |
| EP 4822355 A2 | 2026-10-14 | 4 | P0DMV9 | Espacenet |
| JP 2026086489 A | 2026-05-26 | 11 | P0DMV8 | Espacenet |
| JP 2026086489 A | 2026-05-26 | 11 | P0DMV9 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 48739 | P0DMV8 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 48739 | P0DMV9 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 48744 | P0DMV8 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 48744 | P0DMV9 | Espacenet |
1 to 10 of 670
See all 670 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| CD24FC | CHEMBL4297717 | Heat shock 70 kDa protein 1A/1B inhibitor | INHIBITOR |
Source ChEMBL
Trials3
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT04317040 | CD24FC | PHASE3 | 2021-10-15 | ClinicalTrials.gov |
| NCT04060407 | CD24FC | PHASE1/PHASE2 | ClinicalTrials.gov | |
| NCT03960541 | CD24FC | PHASE2 | 2022-06-08 | ClinicalTrials.gov |
NIH grants1,699
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HSPA1B papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| R01GM058460 | Chromatin Domain Structure and Function | 5 | 2025 |
| R01NS059690 | Molecular Chaperones and Small Molecules | 5 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 4 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 4 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 4 | 2025 |
| P30CA051008 | Georgetown University Lombardi Comprehensive Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,699Source NIH's project files
See all 1,699 nih grantsPapers2,276
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cell-Type-Specific HSPA1B Expression Links COPD and Atherosclerosis. | Immun Inflamm Dis | 2026 | 42806886 | PubTator, text mining | PubMed |
| Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage-Specific Vulnerabilities in Alzheimer's Disease. | Adv Sci (Weinh) | 2026 | 42750204 | PubTator, text mining | PubMed |
| Exploratory Cross-Cohort Transcriptomic Comparison of Coronary Artery Disease and Non-Obstructive Azoospermia. | Int J Mol Sci | 2026 | 42737806 | PubTator, text mining | PubMed |
| PRRSV N protein antagonizes host antiviral immune responses by upregulating HSPA1B to induce autophagic degradation of Fos-related antigen 1. | mBio | 2026 | 42627167 | PubTator, text mining | PubMed |
| Stage-Specific Gene Expression Profiles in Multiple Sclerosis Cortical Lesions Identified via Spatial Transcriptomics. | OMICS | 2026 | 42605943 | PubTator, text mining | PubMed |
| Nuclear speckle-associated perispeckle networks partition active chromatin into gene expression niches. | Cell Rep | 2026 | 42603274 | PubTator, text mining | PubMed |
| CFTR functions as a tumor suppressor in adenoid cystic carcinoma and its silencing reveals an associated vulnerability involving the Hsp70 chaperone system. | Front Oncol | 2026 | 42518810 | PubTator, text mining | PubMed |
| Genetic Analysis of the HSPA1A, HSPA1B, and HSPA1L Genes in Patients with Schizophrenia from Taiwan. | Genes (Basel) | 2026 | 42510767 | PubTator, text mining | PubMed |
| Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production. | Biotechnol Bioeng | 2026 | 42478279 | PubTator, text mining | PubMed |
| Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS-CT1 Study. | Ann Clin Transl Neurol | 2026 | 42420815 | PubTator, text mining | PubMed |
1 to 10 of 2,276
See all 2,276 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3304
GET https://conductscience.org/api/genes/v1/3304/patents?page=2