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HSPA4: heat shock protein family A (Hsp70) member 4

1 protein, 64 patents, 0 drugs, 0 trials, 10,843 NIH grants and 30,022 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHSPA4HGNC
Nameheat shock protein family A (Hsp70) member 4HGNC
NCBI Gene ID3308NCBI Gene
HGNC IDHGNC:5237HGNC
EnsemblENSG00000170606NCBI Gene
AliasesAPG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RYNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P34932Heat shock 70 kDa protein 48400Ensembl, GeneID, HGNCUniProt

Patents 64

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448793P34932Espacenet
EP 4650780 A22025-11-194180P34932Espacenet
EP 4641201 A22025-10-293738P34932Espacenet
EP 4582098 A22025-07-091364P34932Espacenet
JP 2025517969 A2025-06-123738P34932Espacenet
JP 2025517970 A2025-06-124180P34932Espacenet
JP 2025032204 A2025-03-1129717P34932Espacenet
KR 1020250020708 A2025-02-1113P34932Espacenet
JP 2024167327 A2024-12-0313P34932Espacenet
EP 4461818 A22024-11-1329717P34932Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 10843

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01NS059690Molecular Chaperones and Small Molecules922,025NIH's project files
P30CA016672Cancer Center Support Grant792,025NIH's project files
P30CA008748Cancer Center Support Grant702,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant342,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant322,025NIH's project files
ZIASC010074HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction312,025NIH's project files
P30ES006694Southwest Environmental Health Sciences Center302,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program282,025NIH's project files
P30CA047904Cancer Center Support Grant282,025NIH's project files
P50CA098252SPORE in Cervical Cancer252,025NIH's project files

Papers 30022

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817624PubTator, text miningPubMed
42813347PubTator, text miningPubMed
42812611PubTator, text miningPubMed
42811766PubTator, text miningPubMed
42808411PubTator, text miningPubMed
42801363PubTator, text miningPubMed
42787484PubTator, text miningPubMed
42782753PubTator, text miningPubMed
42780555PubTator, text miningPubMed
42770272PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license