ConductScience.org, home

Library / Genes

XIAP: X-linked inhibitor of apoptosis

1 protein, 121 patents, 0 drugs, 0 trials, 4,536 NIH grants and 12,699 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolXIAPHGNC
NameX-linked inhibitor of apoptosisHGNC
NCBI Gene ID331NCBI Gene
HGNC IDHGNC:592HGNC
EnsemblENSG00000101966NCBI Gene
AliasesAPI3, BIRC4, IAP-3, ILP-1, ILP1, MIHA, XLP2, hIAP-3, hIAP3, hILPNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P98170E3 ubiquitin-protein ligase XIAP49774Ensembl, GeneID, HGNCUniProt

Patents 121

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026523243 A2026-07-13107P98170Espacenet
JP 2026516229 A2026-05-20107P98170Espacenet
EP 4705323 A12026-03-11107P98170Espacenet
JP 2026504440 A2026-02-05107P98170Espacenet
KR 1020250177382 A2025-12-235P98170Espacenet
EP 4658677 A22025-12-10107P98170Espacenet
EP 4650780 A22025-11-197195P98170Espacenet
JP 2025517970 A2025-06-127195P98170Espacenet
JP 2025038035 A2025-03-184372P98170Espacenet
EP 4482821 A12025-01-019P98170Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4536

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1422,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028292,025NIH's project files
P30CA008748Cancer Center Support Grant262,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant242,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase162,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant152,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant142,025NIH's project files
P30CA016058Cancer Center Support Grant132,025NIH's project files
R01DK057819Intestinal Mucosal Growth in Health and Surgical Diseases122,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)112,025NIH's project files

Papers 12699

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818383PubTator, text miningPubMed
42810781PubTator, text miningPubMed
42773187PubTator, text miningPubMed
42771130PubTator, text miningPubMed
42771080PubTator, text miningPubMed
42726157PubTator, text miningPubMed
42724498PubTator, text miningPubMed
42688150PubTator, text miningPubMed
42672129PubTator, text miningPubMed
42656404PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license