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Gene · 3310

HSPA6: heat shock protein family A (Hsp70) member 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HSPA6: heat shock protein family A (Hsp70) member 6. Genes, record 3310. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3310

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Gene

Symbol
HSPA6
HGNC
Name
heat shock protein family A (Hsp70) member 6
HGNC
NCBI Gene ID
3310
NCBI Gene
HGNC ID
HGNC:5239
HGNC
Ensembl
ENSG00000173110
NCBI Gene
Aliases
HSP70B'
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P17066Heat shock 70 kDa protein 66431Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448798P17066Espacenet
WO 2024242202 A2024-11-288P17066Espacenet
US 11694765 B22023-07-0410P17066Espacenet
US 11542490 B22023-01-0357P17066Espacenet
US 11446398 B22022-09-2037366P17066Espacenet
JP 2022524081 A2022-04-27140337P17066Espacenet
US 11105809 B22021-08-317P17066Espacenet
US 11078247 B22021-08-035217P17066Espacenet
JP 2020072653 A2020-05-14219P17066Espacenet
US 10352947 B22019-07-1642P17066Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants932

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHSPA6 papersNewest fiscal year
P30ES006694Southwest Environmental Health Sciences Center222025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant202025
T32ES007091Training in Environmental Toxicology of Human Disease122025
P30CA016672Cancer Center Support Grant62025
R01NS059690Molecular Chaperones and Small Molecules62025
P30CA016087Cancer Center Support Grant42025
P20GM103436IDeA Networks of Biomedical Research Excellence in Kentucky32025
P30CA008748Cancer Center Support Grant32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA062203Cancer Center Support Grant32025

1 to 10 of 932Source NIH's project files

See all 932 nih grants

Papers1,278

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
CSF proteomic quantitative trait loci mapping reveals genetic insights into Alzheimer's disease.Mol Neurodegener Adv202642761049PubTator, text miningPubMed
Integration of Spatial Transcriptomics and Mendelian Randomization Identifies Candidate Molecular Regulators of Endometrial Cancer Progression.Cells202642738853PubTator, text miningPubMed
Genetic Variants in HSP70 Family and BAG Co-Chaperone Genes: Associations with Coronary Artery Disease Risk and Potential Regulatory Effects.Int J Mol Sci202642653304PubTator, text miningPubMed
Fascin-Centred Invasive Competence in Eutopic Endometrium: A Hypothesis-Driven Narrative Review of Endometriosis Pathogenesis and Non-Surgical Biomarker Potential.Int J Mol Sci202642653239PubTator, text miningPubMed
Human Hsp70 paralogs display selective J-domain interactions tuning proteostasis under stress.Proc Natl Acad Sci U S A202642612003PubTator, text miningPubMed
RNA-Binding Protein RBMS3 Inhibits Cervical Cancer Progression by Enhancing HSPA6 mRNA Stability.Front Biosci (Landmark Ed)202642530257PubTator, text miningPubMed
Ferroptosis-associated ALOX12 suppresses ovarian cancer progression through MAPK signaling pathway.Tissue Cell202642526085PubTator, text miningPubMed
CFTR functions as a tumor suppressor in adenoid cystic carcinoma and its silencing reveals an associated vulnerability involving the Hsp70 chaperone system.Front Oncol202642518810PubTator, text miningPubMed
Cross-talk between Schwann Cells and CD4+ T Cells Promotes Perineural Invasion in Colorectal Cancer.Cancer Res202642489533PubTator, text miningPubMed
Construction and mechanism of histone deacetylation related gene prognosis model in esophageal carcinoma.Sci Rep202642471418PubTator, text miningPubMed

1 to 10 of 1,278

See all 1,278 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3310

GET https://conductscience.org/api/genes/v1/3310/patents?page=2