Gene · 3313
HSPA9: heat shock protein family A (Hsp70) member 9
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. HSPA9: heat shock protein family A (Hsp70) member 9. Genes, record 3313. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3313
On this page
Gene
- Aliases
- CRP40, CSA, EVPLS, GRP-75, GRP75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74, SAAN, SIDBA4, mot-2, mt-HSP70, mthsp75
- NCBI Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P38646 | Stress-70 protein, mitochondrial | 679 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents121
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 48807 | P38646 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3800 | P38646 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3369 | P38646 | Espacenet |
| WO 2025183089 A | 2025-09-04 | 3 | P38646 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3369 | P38646 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3800 | P38646 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 29741 | P38646 | Espacenet |
| WO 2024242202 A | 2024-11-28 | 10 | P38646 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 29741 | P38646 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1498 | P38646 | Espacenet |
1 to 10 of 121
See all 121 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,948
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HSPA9 papers | Newest fiscal year |
|---|---|---|---|
| R01NS059690 | Molecular Chaperones and Small Molecules | 22 | 2025 |
| ZIAHD008814 | Mammalian iron-sulfur cluster biogenesis | 16 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 14 | 2025 |
| ZIAHD001602 | Regulation Of Intracellular Iron Metabolism | 10 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 6 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 5 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 4 | 2025 |
| R01NS095892 | IMPACTING MITOCHONDRIAL FUNCTION THROUGH ALTERED PROTEASE ACTIVITY | 4 | 2025 |
1 to 10 of 1,948Source NIH's project files
See all 1,948 nih grantsPapers3,383
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A programmable spatiotemporal bioelectrical conduit promotes peripheral nerve regeneration by suppressing ferroptosis through modulation of ER-mitochondria coupling in Schwann cells. | Bioact Mater | 2027 | 42781229 | PubTator, text mining | PubMed |
| Proteomic Signatures of Noise-Induced Hearing Loss in the Mouse Cochlea. | Cell Biol Int | 2026 | 42820356 | PubTator, text mining | PubMed |
| Extracellular vesicles in cancer-associated cachexia: molecular mechanisms and therapeutic perspectives. | Front Cell Dev Biol | 2026 | 42798761 | PubTator, text mining | PubMed |
| Mitochondrial Ca2+ homeostasis in ovarian function and oocyte competence: from molecular transporters to early embryonic development. | Front Cell Dev Biol | 2026 | 42798439 | PubTator, text mining | PubMed |
| DISC1 Orchestrates Mitochondrial Calcium Overload in Diabetic Encephalopathy Through a Dual Nucleocytoplasmic Mechanism. | Biomolecules | 2026 | 42793198 | PubTator, text mining | PubMed |
| PADI-dependent mitochondrial adaptation drives resistance to KRAS inhibitors. | Cell Rep | 2026 | 42758593 | PubTator, text mining | PubMed |
| Effects of homozygous PARK7 gene mutations L166P and M26I on BNIP3/BNIP3L interactions and ER-mitochondria proximity. | Biol Direct | 2026 | 42723107 | PubTator, text mining | PubMed |
| Bardoxolone methyl induces mitochondrial dysfunction, activation of the cytosolic stress response, and increased chaperone capacity in SH-SY5Y cells. Focus on mitochondrial protease LONP1. | Gen Physiol Biophys | 2026 | 42717783 | PubTator, text mining | PubMed |
| Decoding the bile acid-mitochondria axis: Implications for disease management and therapeutic opportunities. | Pharmacol Res | 2026 | 42668075 | PubTator, text mining | PubMed |
| Loss of TIMM8A Inhibits Breast Cancer Progression Through Promoting HSPA9 Ubiquitination and Degradation via Competitive Interaction with RNF4. | Int J Mol Sci | 2026 | 42653385 | PubTator, text mining | PubMed |
1 to 10 of 3,383
See all 3,383 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3313
GET https://conductscience.org/api/genes/v1/3313/patents?page=2