Gene · 3316
HSPB2: heat shock protein family B (small) member 2
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. HSPB2: heat shock protein family B (small) member 2. Genes, record 3316. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3316
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16082 | Heat shock protein beta-2 | 182 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents46
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4762184 A2 | 2026-06-24 | 102 | Q16082 | Espacenet |
| EP 4762184 A2 | 2026-06-24 | 19 | Q16082 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4140 | Q16082 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4140 | Q16082 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 12938 | Q16082 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 1704 | Q16082 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 1706 | Q16082 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 5239 | Q16082 | Espacenet |
| US 11564998 B2 | 2023-01-31 | 8747 | Q16082 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 37307 | Q16082 | Espacenet |
1 to 10 of 46
See all 46 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,748
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | HSPB2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 7 | 2025 |
| R01NS059690 | Molecular Chaperones and Small Molecules | 7 | 2025 |
| P30CA054174 | Mays Cancer Center at UT Health SA | 5 | 2025 |
| P30EY010572 | Ophthalmology Core Facility | 5 | 2025 |
| P30EY011373 | CWRU NEI Vision Center Core Grant | 5 | 2025 |
| ZIASC010074 | HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction | 5 | 2025 |
| P30EY003790 | Core Grant for Vision Research | 4 | 2025 |
1 to 10 of 1,748Source NIH's project files
See all 1,748 nih grantsPapers3,243
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Microtubule Cytoskeleton Dysfunction in Chronic Pain: Mechanisms of Transport Failure and Emerging Therapeutic Targets. | Int J Mol Sci | 2026 | 42794564 | PubTator, text mining | PubMed |
| Centrosome linker protein CEP68 modulates cellular stress responses via nuclear condensate formation and HSP27 interaction. | iScience | 2026 | 42382991 | PubTator, text mining | PubMed |
| Beyond KEAP1: The Context-Specific NRF2 Partner Code in Disease and Therapy. | Antioxidants (Basel) | 2026 | 42352065 | PubTator, text mining | PubMed |
| HSP27 in autoimmune diseases: Context-dependent regulation and clinical potential. | Biochim Biophys Acta Mol Basis Dis | 2026 | 42342167 | PubTator, text mining | PubMed |
| Glutathione-conjugated gold nanoparticles mitigate amyloid-beta-induced neuroinflammation and tauopathy through inhibition of NF-κB, the NLRP3 inflammasome axis in 3D human neural stem cell models. | Exp Cell Res | 2026 | 41997281 | PubTator, text mining | PubMed |
| Olfactory Receptor Activation Reduces Platelet Reactivity and Arterial Thrombosis Through Actin Cytoskeleton Remodeling. | Circulation | 2026 | 41944007 | PubTator, text mining | PubMed |
| NRF2 Stabilization by Isoform-Specific Nuclear Phosphoinositides in Stress Response. | Oral Sci Homeost Med | 2026 | 41908074 | PubTator, text mining | PubMed |
| Molecular and Functional Platelet Abnormalities in Myeloproliferative Neoplasms. | Cells | 2026 | 41892345 | PubTator, text mining | PubMed |
| Chaperone proteins protect against desmin fragment amyloid aggregation. | Biophys J | 2026 | 41877486 | PubTator, text mining | PubMed |
| A bile acid-GPBAR1 network supports anti-inflammatory and anti-fibrotic benefits of probiotics in colitis. | Gut Microbes | 2026 | 41851067 | PubTator, text mining | PubMed |
1 to 10 of 3,243
See all 3,243 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3316
GET https://conductscience.org/api/genes/v1/3316/patents?page=2