Gene · 3337
DNAJB1: DnaJ heat shock protein family (Hsp40) member B1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. DNAJB1: DnaJ heat shock protein family (Hsp40) member B1. Genes, record 3337. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3337
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P25685 | DnaJ homolog subfamily B member 1 | 340 | 15 | Ensembl, GeneID, HGNC |
Source UniProt
Patents77
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026120675 A | 2026-07-22 | 779 | P25685 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 44097 | P25685 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1489 | P25685 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4468 | P25685 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1489 | P25685 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 27364 | P25685 | Espacenet |
| KR 1020250020708 A | 2025-02-11 | 16 | P25685 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4468 | P25685 | Espacenet |
| JP 2024167327 A | 2024-12-03 | 16 | P25685 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 27364 | P25685 | Espacenet |
1 to 10 of 77
See all 77 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,534
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | DNAJB1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 24 | 2025 |
| P50CA210964 | Mayo Clinic Hepatobiliary SPORE | 16 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 12 | 2025 |
| R01NS059690 | Molecular Chaperones and Small Molecules | 11 | 2025 |
| R15GM110606 | J-Protein Regulation of Yeast Prion Propagation | 9 | 2025 |
| R01AR068797 | Chaperone Dysfunction in Myopathy: Connecting Yeast Genetics with Mouse Models | 7 | 2025 |
| R35GM130389 | Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches | 6 | 2025 |
| ZIADK024950 | Prions of Yeast and Anti-Prion Systems | 6 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 5 | 2025 |
1 to 10 of 1,534Source NIH's project files
See all 1,534 nih grantsPapers2,173
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multi-Omics Analysis and Experimental Validation Uncover Neddylation-Associated Biomarkers and Cellular Landscape in Lung Adenocarcinoma. | Front Biosci (Landmark Ed) | 2026 | 42811976 | PubTator, text mining | PubMed |
Detection of Low Levels of DNAJB1::PRKACA Fusion KinaseRequires the Utilization of Sensitive Assays and CarefulMethodological Planning. Reply to Palaz et al. Independent Multi-Cohort RNA-Seq Analysis Does Not Support Recurrent DNAJB1::PRKACA Fusion in Hepatoblastoma or Biliary Atresia. Comment on "Fleifil et al. DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways. Cancers 2025, 17, 83". | Cancers (Basel) | 2026 | 42650017 | PubTator, text mining | PubMed |
Independent Multi-Cohort RNA-Seq Analysis Does Not Support Recurrent DNAJB1::PRKACA Fusion in Hepatoblastoma or Biliary Atresia. Comment on Fleifil et al. DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways. Cancers 2025, 17, 83. | Cancers (Basel) | 2026 | 42649992 | PubTator, text mining | PubMed |
| Management of rare primary liver cancers: combined hepato-cholangiocarcinoma and fibrolamellar hepatocellular carcinoma. | JHEP Rep | 2026 | 42595050 | PubTator, text mining | PubMed |
| Novel Insights into the Human Hsc70 Structure by Cross-Linking Mass Spectrometry and Molecular Modeling. | J Proteome Res | 2026 | 42565729 | PubTator, text mining | PubMed |
| Single-cell RNA sequencing reveals immunological heterogeneity of the tumor microenvironment in acute myeloid leukemia. | Adv Clin Exp Med | 2026 | 42524819 | PubTator, text mining | PubMed |
| Dynamic m6A epitranscriptomic remodeling coordinates host transcriptional reprogramming during MPXV infection. | Cell Commun Signal | 2026 | 42469869 | PubTator, text mining | PubMed |
| Discovery of hub genes linking oxidative stress to type 2 diabetic sarcopenia using single-cell sequencing and machine learning. | PLoS One | 2026 | 42412755 | PubTator, text mining | PubMed |
| Functional Precision Oncology in Fibrolamellar Carcinoma: Ex Vivo Identification of Therapeutic Vulnerabilities. | Cancers (Basel) | 2026 | 42279327 | PubTator, text mining | PubMed |
| Human J-domain proteins promote stress granule disassembly and suppress neurodegeneration-linked protein aggregation. | Cell Rep | 2026 | 42262924 | PubTator, text mining | PubMed |
1 to 10 of 2,173
See all 2,173 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3337
GET https://conductscience.org/api/genes/v1/3337/patents?page=2