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HSPG2: heparan sulfate proteoglycan 2

1 protein, 39 patents, 0 drugs, 0 trials, 4,088 NIH grants and 7,296 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHSPG2HGNC
Nameheparan sulfate proteoglycan 2HGNC
NCBI Gene ID3339NCBI Gene
HGNC IDHGNC:5273HGNC
EnsemblENSG00000142798NCBI Gene
AliasesHSPG, PLC, PRCAN, SJA, SJS, SJS1, perlecanNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P98160Basement membrane-specific heparan sulfate proteoglycan core protein4,3912Ensembl, GeneID, HGNCUniProt

Patents 39

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1448928P98160Espacenet
EP 4650780 A22025-11-199507P98160Espacenet
EP 4641201 A22025-10-299754P98160Espacenet
EP 4641203 A22025-10-29279P98160Espacenet
EP 4626456 A12025-10-081P98160Espacenet
JP 2025147176 A2025-10-066611P98160Espacenet
JP 2025529142 A2025-09-046622P98160Espacenet
US 12371689 B22025-07-296622P98160Espacenet
JP 2025517967 A2025-06-12279P98160Espacenet
JP 2025517969 A2025-06-129754P98160Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4088

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant182,025NIH's project files
P30CA016672Cancer Center Support Grant122,025NIH's project files
ZIADK053101Cellular Basis Of Action Of Gastrointestinal Peptides/Growth factors92,025NIH's project files
ZIAHD000196Phosphoinositide-calcium Signaling In Cell Regulation82,025NIH's project files
ZIADK053100Characterization And Pharmacology Of Receptors For Gastrointestinal Peptides72,025NIH's project files
P20GM103446Delaware INBRE62,025NIH's project files
P30CA014051Cancer Center Support (Core) Grant62,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant62,025NIH's project files
P30CA138313Medical University of South Carolina - Cancer Center Support Grant62,025NIH's project files
R01DE017102TRPC1, Calcium, and Saliva Secretion62,025NIH's project files

Papers 7296

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42803182PubTator, text miningPubMed
42797422PubTator, text miningPubMed
42792867PubTator, text miningPubMed
42776569PubTator, text miningPubMed
42776288PubTator, text miningPubMed
42759407PubTator, text miningPubMed
42740052PubTator, text miningPubMed
42718790PubTator, text miningPubMed
42695902PubTator, text miningPubMed
42643032PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license