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HTR4: 5-hydroxytryptamine receptor 4
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Gene · 3360

Papers1,853

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,853

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TitleJournalYearPMIDFound bySource
Spatial correspondence between altered brain function and normative neurotransmitter density maps in Type 1 diabetes mellitus.J Endocrinol Invest202642667349PubTator, text miningPubMed
Exercise-related changes in depressive symptoms and their association with anterior cingulate cortical thickness.Int J Clin Health Psychol202642604120PubTator, text miningPubMed
[Advances in the Treatment of Refractory Pediatric Constipation].Acta Gastroenterol Latinoam202642569715PubTator, text miningPubMed
Mosapride promotes internalization of a TREK1-HTR4 complex and exerts rapid antidepressant-like effects.Mol Psychiatry202642542439PubTator, text miningPubMed
Nature, nurture, and 5-HT4R: Familial predisposition, not parental bonding, is associated with brain 5-HT4R in a sex-specific manner.Psychiatry Clin Neurosci202642541429PubTator, text miningPubMed
Serotonergic Signaling in Gastric Physiology and Motility Disorders.Gastroenterology202642486340PubTator, text miningPubMed
Regulation of spermatozoal capacitation by serotonin.J Reprod Dev202642402414PubTator, text miningPubMed
Effects on hippocampal activity following novel 5-HT4 receptor agonism in unmedicated patients with depression: the RESTAND study.Transl Psychiatry202642309998PubTator, text miningPubMed
Pro-cognitive effects of 5-HT4 receptor agonism in individuals with remitted depression.Psychol Med202642290157PubTator, text miningPubMed
Selective molecular and network architecture features underlie brain cortical atrophy in dementia with Lewy bodies.J Biomed Sci202642265698PubTator, text miningPubMed
Early effects of a novel 5-HT4R agonist (PF-04995274) and the SSRI citalopram on emotional cognition in unmedicated depression: RESTAND study.Br J Psychiatry202642204761PubTator, text miningPubMed
Serotonin and working memory in mood disorder and healthy states: multi-cohort positron emission tomography study.BJPsych Open202642179183PubTator, text miningPubMed
Low 5HT1B and 5HT4 Receptor Neurotransmission as a Potential Link Between Cholesterol Metabolism and Suicide Risk.J Neurochem202642130235PubTator, text miningPubMed
Structural connectome architecture and biological vulnerability shape cortical atrophy in cocaine use disorder.BMC Med202642106690PubTator, text miningPubMed
Correspondence of Basal Forebrain Resting-State Functional Connectivity and Cerebral Glucose Metabolism Alterations With Neurotransmitter Maps in Alzheimer's Disease.CNS Neurosci Ther202642104858PubTator, text miningPubMed
Serotonergic Regulation of Nicotine Addiction: Receptor-specific Mechanisms and Therapeutic Strategies.Curr Neurovasc Res202642099156PubTator, text miningPubMed
Distinct activity in prefrontal projections promotes temporal control of action.Proc Natl Acad Sci U S A202642090261PubTator, text miningPubMed
Anti-alzheimer Drugs Development and Small Molecules: Mechanistic Understanding of the 5HT₄ and 5-HT₆ Receptor.Curr Neuropharmacol202641935386PubTator, text miningPubMed
Autism and Cortical Thickness Deviation From Neurotypical Controls: Evidence for a Spatial Association With Serotonin Receptors.Autism Res202641923483PubTator, text miningPubMed
Serotonin Associated Mechanisms in Sudden Unexpected Death in Epilepsy: A Review.Rev Neurol202641914335PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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