Gene · 337
APOA4: apolipoprotein A4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. APOA4: apolipoprotein A4. Genes, record 337. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/337
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P06727 | Apolipoprotein A-IV | 396 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents37
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 37645 | P06727 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7480 | P06727 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1115 | P06727 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7453 | P06727 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 943 | P06727 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1115 | P06727 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7453 | P06727 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7480 | P06727 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 5670 | P06727 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 943 | P06727 | Espacenet |
1 to 10 of 37
See all 37 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,802
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | APOA4 papers | Newest fiscal year |
|---|---|---|---|
| P30DK017047 | Diabetes Research Center | 12 | 2025 |
| P01HL128203 | Multi-disciplinary Approaches to HDL Structure, Assembly, and Functional Heterogeneity | 7 | 2025 |
| P30DK035816 | Nutrition Obesity Research Center | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30DK056341 | Washington University Nutrition Obesity Research Center | 5 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 5 | 2025 |
| P01HL116263 | HDL Function in Human Disease | 4 | 2025 |
| P01HL151328 | Triglycerides, Diabetes and Cardiovascular Disease | 4 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 4 | 2025 |
| P50CA186781 | Mayo Clinic Multiple Myeloma SPORE | 4 | 2025 |
1 to 10 of 1,802Source NIH's project files
See all 1,802 nih grantsPapers3,283
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| From Machine Learning-Enhanced Proteomics to a Validated Diagnostic Model: A Pipeline for Breast Cancer Biomarker Discovery via Independent and Transcriptomic Corroboration. | Bioengineering (Basel) | 2026 | 42791912 | PubTator, text mining | PubMed |
| 3 Discordant Extracardiac Amyloid Proteins Highlighting Bystander Deposition in a Case of Light-Chain Amyloid Cardiomyopathy. | JACC Case Rep | 2026 | 42782045 | PubTator, text mining | PubMed |
| Apolipoprotein A-IV Cardiac Amyloidosis as a Diagnostic Pitfall: Beyond the Noninvasive Algorithm. | JACC Case Rep | 2026 | 42782043 | PubTator, text mining | PubMed |
| Apolipoprotein A-IV Cardiac Amyloidosis: Beyond ATTR and AL. | JACC Case Rep | 2026 | 42782041 | PubTator, text mining | PubMed |
| Apolipoprotein A-IV Cardiac Amyloidosis Presenting as Massive Ventricular Wall Thickening Mimicking Hypertrophic Cardiomyopathy. | JACC Case Rep | 2026 | 42782023 | PubTator, text mining | PubMed |
| Clinical and Proteomic Biomarkers of Trifluridine/Tipiracil in Fluoropyrimidine-Refractory Advanced Pancreatic Adenocarcinoma: A Single-Arm Phase II Trial. | JCO Precis Oncol | 2026 | 42777178 | PubTator, text mining | PubMed |
| Dietary Patterns Are Key Predictors of Cardiovascular Risk Beyond Genetic Risk Across Metabolic Syndrome Trajectories in A Korean Prospective Cohort Study. | J Nutr | 2026 | 42772683 | PubTator, text mining | PubMed |
| Plasma Proteomic Profiling of Comorbid and Noncomorbid COVID-19 Patients in ICU. | J Proteome Res | 2026 | 42695888 | PubTator, text mining | PubMed |
| Plasma apolipoprotein A-IV deficiency as a proteomics-identified diagnostic biomarker for heat stroke: A prospective 2-center study. | Chin J Traumatol | 2026 | 42557209 | PubTator, text mining | PubMed |
| Proteomic analysis of corneal astigmatism identifies reduced apolipoprotein A-IV as a candidate biomarker. | Front Med (Lausanne) | 2026 | 42529179 | PubTator, text mining | PubMed |
1 to 10 of 3,283
See all 3,283 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/337
GET https://conductscience.org/api/genes/v1/337/patents?page=2