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TNC: tenascin C

1 protein, 154 patents, 4 drugs, 7 trials, 5,534 NIH grants and 11,695 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTNCHGNC
Nametenascin CHGNC
NCBI Gene ID3371NCBI Gene
HGNC IDHGNC:5318HGNC
EnsemblENSG00000041982NCBI Gene
Aliases150-225, DFNA56, GMEM, GP, HXB, JI, MGC167029, TN, TN-CNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P24821Tenascin2,20121Ensembl, GeneID, HGNCUniProt

Patents 154

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026121199 A2026-06-118P24821Espacenet
JP 2026015326 A2026-01-2975P24821Espacenet
JP 2026004568 A2026-01-1466717P24821Espacenet
EP 4650780 A22025-11-192445P24821Espacenet
EP 4641201 A22025-10-292028P24821Espacenet
JP 2025147176 A2025-10-0613550P24821Espacenet
JP 2025529142 A2025-09-047933P24821Espacenet
US 12371689 B22025-07-297933P24821Espacenet
JP 2025517969 A2025-06-122028P24821Espacenet
JP 2025517970 A2025-06-122445P24821Espacenet

Drugs 4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
81C6 131ICHEMBL2109582Tenascin binding agentBINDING AGENTChEMBL
F16IL2CHEMBL2109583Tenascin otherOTHERChEMBL
F16SIP 131ICHEMBL2109584Tenascin binding agentBINDING AGENTChEMBL
TENATUMOMABCHEMBL1743077Tenascin otherOTHERChEMBL

Trials 7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05468294F16IL2PHASE1/PHASE2ClinicalTrials.gov
NCT03207191F16IL2PHASE1ClinicalTrials.gov
NCT02957032F16IL2PHASE1ClinicalTrials.gov
NCT02602067TENATUMOMABPHASE1ClinicalTrials.gov
NCT02054884F16IL2PHASE2ClinicalTrials.gov
NCT01134250F16IL2PHASE1/PHASE2ClinicalTrials.gov
NCT01131364F16IL2PHASE1/PHASE2ClinicalTrials.gov

NIH grants 5534

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant352,025NIH's project files
P30CA016672Cancer Center Support Grant202,025NIH's project files
P30EY010572Ophthalmology Core Facility172,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
P30CA006973Regional Oncology Research Center122,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support122,025NIH's project files
R01HL076246Chemokines in healing myocardial infarction112,025NIH's project files
R01HL085440Resolution of inflammation in healing myocardial infarcts112,025NIH's project files
P20GM103446Delaware INBRE102,025NIH's project files
P30CA014051Cancer Center Support (Core) Grant102,025NIH's project files

Papers 11695

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42815077PubTator, text miningPubMed
42804341PubTator, text miningPubMed
42792700PubTator, text miningPubMed
42780918PubTator, text miningPubMed
42780910PubTator, text miningPubMed
42774130PubTator, text miningPubMed
42773217PubTator, text miningPubMed
42759446PubTator, text miningPubMed
42737697PubTator, text miningPubMed
42710793PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license