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ICAM1: intercellular adhesion molecule 1

1 protein, 211 patents, 5 drugs, 8 trials, 18,778 NIH grants and 56,622 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolICAM1HGNC
Nameintercellular adhesion molecule 1HGNC
NCBI Gene ID3383NCBI Gene
HGNC IDHGNC:5344HGNC
EnsemblENSG00000090339NCBI Gene
AliasesBB2, CD54, P3.58NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05362Intercellular adhesion molecule 153214Ensembl, GeneID, HGNCUniProt

Patents 211

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026193010 A22026-09-1716P05362Espacenet
JP 2026122034 A2026-07-2723P05362Espacenet
JP 2026074200 A2026-05-0113P05362Espacenet
US 12601751 B22026-04-144P05362Espacenet
US 12595486 B22026-04-07213P05362Espacenet
EP 4712986 A12026-03-2547P05362Espacenet
EP 4687959 A12026-02-115P05362Espacenet
JP 2026004568 A2026-01-1450020P05362Espacenet
JP 2026500896 A2026-01-092P05362Espacenet
JP 2026500455 A2026-01-071P05362Espacenet

Drugs 5

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ALICAFORSENCHEMBL2108326Intercellular adhesion molecule-1 mRNA 3'UTR antisense inhibitorANTISENSE INHIBITORChEMBL
ALICAFORSEN SODIUMCHEMBL2108895Intercellular adhesion molecule-1 mRNA 3'UTR antisense inhibitorANTISENSE INHIBITORChEMBL
BI-505CHEMBL2109482Intercellular adhesion molecule-1 antagonistANTAGONISTChEMBL
ENLIMOMABCHEMBL2109090Intercellular adhesion molecule-1 inhibitorINHIBITORChEMBL
ENLIMOMAB PEGOLCHEMBL2108401Intercellular adhesion molecule-1 antagonistANTAGONISTChEMBL

Trials 8

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02756728BI-505PHASE1/PHASE2ClinicalTrials.gov
NCT02525523ALICAFORSENPHASE32020-02-25ClinicalTrials.gov
NCT01838369BI-505PHASE2ClinicalTrials.gov
NCT01025206BI-505PHASE1ClinicalTrials.gov
NCT00063830ALICAFORSENPHASE2ClinicalTrials.gov
NCT00063414ALICAFORSENPHASE2ClinicalTrials.gov
NCT00048295ALICAFORSENPHASE3ClinicalTrials.gov
NCT00048113ALICAFORSENPHASE3ClinicalTrials.gov

NIH grants 18778

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant922,025NIH's project files
P30CA008748Cancer Center Support Grant812,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award402,025NIH's project files
ZIABC010666Cancer Immunotherapy402,025NIH's project files
P30CA006973Regional Oncology Research Center352,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant302,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support292,025NIH's project files
P30CA016058Cancer Center Support Grant252,025NIH's project files
P30CA047904Cancer Center Support Grant252,025NIH's project files
ZIABC010661Vaccine and Drug Combination Therapy for Human Cancers252,025NIH's project files

Papers 56622

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820599PubTator, text miningPubMed
42815837PubTator, text miningPubMed
42806711PubTator, text miningPubMed
42800691PubTator, text miningPubMed
42799997PubTator, text miningPubMed
42798949PubTator, text miningPubMed
42798836PubTator, text miningPubMed
42793832PubTator, text miningPubMed
42793190PubTator, text miningPubMed
42792898PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license