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Gene · 3384

ICAM2: intercellular adhesion molecule 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ICAM2: intercellular adhesion molecule 2. Genes, record 3384. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3384

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Gene

Symbol
ICAM2
HGNC
Name
intercellular adhesion molecule 2
HGNC
NCBI Gene ID
3384
NCBI Gene
HGNC ID
HGNC:5345
HGNC
Ensembl
ENSG00000108622
NCBI Gene
Aliases
CD102
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13598Intercellular adhesion molecule 22751Ensembl, GeneID, HGNC

Source UniProt

Patents114

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450022P13598Espacenet
JP 2026004568 A2026-01-1450023P13598Espacenet
JP 2026004568 A2026-01-1450024P13598Espacenet
JP 2026004568 A2026-01-1450025P13598Espacenet
JP 2026004568 A2026-01-1450026P13598Espacenet
JP 2026500896 A2026-01-093P13598Espacenet
EP 4650780 A22025-11-1912260P13598Espacenet
WO 2025235604 A12025-11-133P13598Espacenet
WO 2025235605 A12025-11-133P13598Espacenet
WO 2025228986 A12025-11-0618P13598Espacenet

1 to 10 of 114

See all 114 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,443

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleICAM2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant82025
P30CA008748Cancer Center Support Grant52025
P30CA023108Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025
ZIABC005645Role of the HTLV-1A and HTLV1-C inflammatory profile in disease42025
P30CA016087Cancer Center Support Grant32025
P30CA021765Cancer Center Support Grant (CCSG)32025
R37AI049653Differentiation and Function of Monocytes and Macrophages32025
ZICBC010936Building 41 Flow Cytometry Core32025
P01AI039671Costimulatory Mechanisms of Autoimmunity22025

1 to 10 of 1,443Source NIH's project files

See all 1,443 nih grants

Papers2,060

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Combination of Blastocyst Complementation and Omics Allows Fast Evaluation of Human Pathogenic Mutations in Mice.Am J Respir Cell Mol Biol202642814875PubTator, text miningPubMed
Clerodendrum japonicum Extract Suppresses the Pathogenicity of Rheumatoid Arthritis Fibroblast-Like Synoviocytes by Inhibiting METTL3-Mediated ICAM2 mRNA Methylation.Cell Biochem Funct202642764683PubTator, text miningPubMed
A Cross-Sectional Exploratory Study of Endothelial Biomarkers in Non-Obese Women with and Without Polyendocrine Metabolic Ovarian Syndrome.Int J Mol Sci202642737559PubTator, text miningPubMed
Cycloechinulin inhibits breast cancer progression via the SGOL2/METTL3/ICAM2 signaling axis and suppresses the growth of breast cancer patient-derived organoids.Cell Signal202642697347PubTator, text miningPubMed
Single-cell transcriptomics reveals cellular heterogeneity and neoadjuvant chemotherapy response signatures in triple-negative breast cancer.Front Oncol202642687923PubTator, text miningPubMed
CircDOPEY2 promotes prostate cancer metastasis via inhibiting heterogeneous nuclear ribonucleoprotein M ubiquitination to stabilize intercellular adhesion molecule 2 mRNA.J Pharmacol Exp Ther202642664534PubTator, text miningPubMed
Visualization of new vessel formation during venous thrombus organization using genetic fate mapping.Res Pract Thromb Haemost202642656861PubTator, text miningPubMed
A Coordinated Adhesion-Molecule Activation Profile in Pediatric Sepsis: A Prospective Cohort Study from Vietnam.Pediatr Rep202642347075PubTator, text miningPubMed
Investigating Immune Microenvironment of Inflammatory Bowel Disease and the Mitochondrial Metabolism-Related Molecular Mechanisms: Combining a Multiomics Approach and Experimental Validation.OMICS202642295138PubTator, text miningPubMed
Integrated single-cell transcriptomic analysis identifies PF4 + /PPBP + megakaryocyte-like granulocytes associated with immune dysregulation in autoimmune diseases.Biochem Biophys Rep202642180183PubTator, text miningPubMed

1 to 10 of 2,060

See all 2,060 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3384

GET https://conductscience.org/api/genes/v1/3384/patents?page=2