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Gene · 3385

ICAM3: intercellular adhesion molecule 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ICAM3: intercellular adhesion molecule 3. Genes, record 3385. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3385

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Gene

Symbol
ICAM3
HGNC
Name
intercellular adhesion molecule 3
HGNC
NCBI Gene ID
3385
NCBI Gene
HGNC ID
HGNC:5346
HGNC
Ensembl
ENSG00000076662
NCBI Gene
Aliases
CD50, CDW50, ICAM-R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32942Intercellular adhesion molecule 35471Ensembl, GeneID, HGNC

Source UniProt

Patents104

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12595486 B22026-04-07231P32942Espacenet
JP 2026004568 A2026-01-1450027P32942Espacenet
JP 2026500896 A2026-01-094P32942Espacenet
EP 4650780 A22025-11-19117P32942Espacenet
WO 2025235604 A12025-11-134P32942Espacenet
WO 2025235605 A12025-11-134P32942Espacenet
EP 4640849 A22025-10-2912P32942Espacenet
EP 4641201 A22025-10-2992P32942Espacenet
JP 2025529142 A2025-09-042026P32942Espacenet
US 12371689 B22025-07-292026P32942Espacenet

1 to 10 of 104

See all 104 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
ICM3CHEMBL2109481Intercellular adhesion molecule 3 inhibitorINHIBITOR

Source ChEMBL

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,126

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleICAM3 papersNewest fiscal year
P30CA016672Cancer Center Support Grant42025
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition42025
P20GM103475Advancing Competitive Biomedical Research in Puerto Rico22025
P30AI027757University of Washington/Fred Hutch Center for AIDS Research22025
P30AI042853Providence/Boston Center for AIDS Research (CFAR)22025
P30AI064518Center for AIDS Research22025
P30CA010815Consolidated Basic Cancer Research Program22025
P30CA014520UW Comprehensive Cancer Center Support22025
P30CA016058Cancer Center Support Grant22025
P30CA046934University of Colorado Cancer Center Support Grant22025

1 to 10 of 1,126Source NIH's project files

See all 1,126 nih grants

Papers1,776

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Development and Validation of an Anoikis-Related Machine Learning Signature for Prognosis and Brain Metastasis-Associated Classification in Lung Adenocarcinoma.Cancers (Basel)202642352501PubTator, text miningPubMed
A Coordinated Adhesion-Molecule Activation Profile in Pediatric Sepsis: A Prospective Cohort Study from Vietnam.Pediatr Rep202642347075PubTator, text miningPubMed
Adhesion molecules and T cell imbalance in severe eosinophilic asthma: Insights from anti-IL-5R treatment.Pulmonology202642324975PubTator, text miningPubMed
TM4SF1 regulates esophageal squamous cell carcinoma KYSE150 cell phenotypes via miRNA-regulated pathways.Cytotechnology202642040328PubTator, text miningPubMed
Sex differences in proteomic response to ischemic stroke.Biol Sex Differ202642002779PubTator, text miningPubMed
RASA2 deletion rescues immune synapse dysfunction, enhancing CAR T cell efficacy against DMGs.J Immunother Cancer202641912267PubTator, text miningPubMed
Solubility based mechanistic profiling of combinatorial drug therapy.Nat Commun202641882025PubTator, text miningPubMed
Aberrant fucosylation of extracellular vesicles remodels the vascular microenvironment and promotes chemoresistance in myelodysplastic syndromes and acute myeloid leukemia.Haematologica202641784036PubTator, text miningPubMed
Marine-Derived Defenses Against HIV: Emerging Bioactive Molecules from the Seas.Mar Drugs202641745473PubTator, text miningPubMed
Innovative approaches targeting innate immune cells to promote organ transplant tolerance.Front Transplant202641737588PubTator, text miningPubMed

1 to 10 of 1,776

See all 1,776 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3385

GET https://conductscience.org/api/genes/v1/3385/patents?page=2