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Gene · 339

APOBEC1: apolipoprotein B mRNA editing enzyme catalytic subunit 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. APOBEC1: apolipoprotein B mRNA editing enzyme catalytic subunit 1. Genes, record 339. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/339

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Gene

Symbol
APOBEC1
HGNC
Name
apolipoprotein B mRNA editing enzyme catalytic subunit 1
HGNC
NCBI Gene ID
339
NCBI Gene
HGNC ID
HGNC:604
HGNC
Ensembl
ENSG00000111701
NCBI Gene
Aliases
APO1, APOBEC-1, BEDP, CDAR1, HEPR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P41238C->U-editing enzyme APOBEC-12361Ensembl, GeneID, HGNC

Source UniProt

Patents219

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4828972 A12026-10-2848P41238Espacenet
EP 4828972 A12026-10-28580P41238Espacenet
JP 2026525611 A2026-07-3182P41238Espacenet
JP 2026525612 A2026-07-31515P41238Espacenet
EP 4777618 A12026-07-2248P41238Espacenet
EP 4777618 A12026-07-22580P41238Espacenet
JP 2026116287 A2026-07-09279P41238Espacenet
EP 4762095 A12026-06-2448P41238Espacenet
EP 4762177 A12026-06-2441P41238Espacenet
EP 4753741 A12026-06-1048P41238Espacenet

1 to 10 of 219

See all 219 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,054

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAPOBEC1 papersNewest fiscal year
P30DK052574Host-environment interactions in the pathophysiology of digestive disease282025
RM1HG009490Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease162025
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)132025
R35GM118062Integrating Chemistry and Evolution to Illuminate Biology and Enable Novel Therapeutics132025
P30CA008748Cancer Center Support Grant82025
P01CA234228APOBEC Mutagenesis in Cancer72025
T32CA009138Molecular, Genetic and Cellular Targets of Cancer Training Program72025
R01AI150524Structural Basis of APOBEC Functions and HIV Restriction62025
P30CA016672Cancer Center Support Grant52025
P30CA036727Buffett Cancer Center Support Grant52025

1 to 10 of 1,054Source NIH's project files

See all 1,054 nih grants

Papers1,336

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
mRNA editing of the Alzheimer's risk gene APOE.bioRxiv202642818221PubTator, text miningPubMed
CRYSPER and CUREIPES: two new molecular tools enabling analysis of RNA splicing and C-to-U RNA editing-inducible protein expression at single cell resolution.Nucleic Acids Res202642779099PubTator, text miningPubMed
Mapping Allele-specific RBP Binding by a Machine Learning Coupled RNA Editing Strategy in Human Embryonic Stem Cells.Genomics Proteomics Bioinformatics202642671340PubTator, text miningPubMed
Potentially regulating the ApoB RNA editosome via FXR activation: The natural compound continentalic acid alleviates hepatic fibrogenesis.Phytomedicine202642462532PubTator, text miningPubMed
Deciphering APOBEC1 in Avians: unravelling loss events and functional insights.Immunogenetics202642289512PubTator, text miningPubMed
Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target.Adv Sci (Weinh)202642085637PubTator, text miningPubMed
The Role of Nuclear APOBEC Enzymes in Neoplastic Progression of Ulcerative Colitis.Clin Exp Gastroenterol202642006844PubTator, text miningPubMed
HAMMER: hairpin-based APOBEC3A-mediated mRNA editing reporter.Nucleic Acids Res202641925228PubTator, text miningPubMed
An efficient C-to-U RNA recorder as a tool for profiling targets of RNA-binding proteins.N Biotechnol202641839235PubTator, text miningPubMed
Reprogramming tumor immunity through APOBEC3s-mediated mutagenesis: from genome instability to immune checkpoint interactions.Front Immunol202641756300PubTator, text miningPubMed

1 to 10 of 1,336

See all 1,336 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/339

GET https://conductscience.org/api/genes/v1/339/patents?page=2