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Gene · 3399

ID3: inhibitor of DNA binding 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ID3: inhibitor of DNA binding 3. Genes, record 3399. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3399

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Gene

Symbol
ID3
HGNC
Name
inhibitor of DNA binding 3
HGNC
NCBI Gene ID
3399
NCBI Gene
HGNC ID
HGNC:5362
HGNC
Ensembl
ENSG00000117318
NCBI Gene
Aliases
HEIR-1, bHLHb25
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q02535DNA-binding protein inhibitor ID-31191Ensembl, GeneID, HGNC

Source UniProt

Patents49

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4756030 A12026-06-106Q02535Espacenet
JP 2026004568 A2026-01-1449755Q02535Espacenet
EP 4650780 A22025-11-199483Q02535Espacenet
EP 4641201 A22025-10-299732Q02535Espacenet
JP 2025147176 A2025-10-0615159Q02535Espacenet
JP 2025517969 A2025-06-129732Q02535Espacenet
JP 2025517970 A2025-06-129483Q02535Espacenet
JP 2025506185 A2025-03-0735Q02535Espacenet
JP 2025028160 A2025-02-2815159Q02535Espacenet
WO 2025033358 A2025-02-136Q02535Espacenet

1 to 10 of 49

See all 49 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,312

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleID3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant322025
P30CA016672Cancer Center Support Grant132025
P01AI102853Molecular Basis for γδ T Lineage Specification102025
U19AI057266Vaccine and Infection Induced Immunity in the Young and Aged82025
P30CA006927Comprehensive Cancer Center Program at Fox Chase72025
P30CA016520Abramson Cancer Center Support Grant72025
T32HL007284Basic Cardiovascular Research Training Grant62025
ZIASC000550Lymphoma Disease Discovery and Definition62025
P01AI039671Costimulatory Mechanisms of Autoimmunity52025
P01CA214278Enhancing Chimeric Antigen Receptor T Cell Therapies for HematologicMalignancies: Beyond CART 1952025

1 to 10 of 2,312Source NIH's project files

See all 2,312 nih grants

Papers2,841

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Statement of retraction: Circadian Period 2 (Per2) downregulate inhibitor of differentiation 3 (Id3) expression via PTEN/AKT/Smad5 axis to inhibits glioma cell proliferation.Bioengineered202642821469PubTator, text miningPubMed
[Correlation Between Molecular Genetic Features and Clinical Prognosis in Pediatric Burkitt Lymphoma].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642802437PubTator, text miningPubMed
The Bath Additive KTPB Induces an Angiogenesis-Associated Transcriptional Program Without Detectable Cytotoxicity in Human Vascular Endothelial Cells.Curr Issues Mol Biol202642793251PubTator, text miningPubMed
Identification of key genes and pathways involved in trastuzumab resistance in HER2-positive gastric cancer through integrative bioinformatics analysis.Iran J Basic Med Sci202642787726PubTator, text miningPubMed
Identification and functional experimental verification of efferocytosis-related diagnostic biomarkers for sepsis.Int J Biochem Cell Biol202642777907PubTator, text miningPubMed
Cancer Stem Cell Quiescence: Molecular and Microenvironmental Evidence for an Actively Regulated Adaptive Survival Strategy.Cancer Med202642768738PubTator, text miningPubMed
ID3-directed sonogenetics to enhance osteogenesis and bone defect healing.Int J Oral Sci202642733085PubTator, text miningPubMed
PTD-FNK Alleviated Heat Stress-Induced Apoptosis of Boar Sertoli Cells via the PI3K/AKT Pathway.Vet Sci202642655818PubTator, text miningPubMed
Non-redundant functions of NFATc1 in survival and NFATc2 in generation of exhausted CD8+ T cells.Front Immunol202642568576PubTator, text miningPubMed
[Analysis of the Gene Mutation Distribution and Its Relationship with Prognosis in Patients with Primary Gastrointestinal Diffuse Large B-Cell Lymphoma by Next Generation Sequencing].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642544655PubTator, text miningPubMed

1 to 10 of 2,841

See all 2,841 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3399

GET https://conductscience.org/api/genes/v1/3399/patents?page=2