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Gene · 3400

ID4: inhibitor of DNA binding 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ID4: inhibitor of DNA binding 4. Genes, record 3400. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3400

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Gene

Symbol
ID4
HGNC
Name
inhibitor of DNA binding 4
HGNC
NCBI Gene ID
3400
NCBI Gene
HGNC ID
HGNC:5363
HGNC
Ensembl
ENSG00000172201
NCBI Gene
Aliases
IDB4, bHLHb27
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P47928DNA-binding protein inhibitor ID-41610Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1449756P47928Espacenet
JP 2025147176 A2025-10-0615160P47928Espacenet
JP 2025032204 A2025-03-1129794P47928Espacenet
JP 2025028160 A2025-02-2815160P47928Espacenet
KR 1020250010750 A2025-01-2115160P47928Espacenet
EP 4461818 A22024-11-1329794P47928Espacenet
JP 2024109657 A2024-08-1414999P47928Espacenet
US 11821003 B22023-11-214P47928Espacenet
JP 2023058610 A2023-04-2529794P47928Espacenet
US 11446398 B22022-09-2040185P47928Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,228

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleID4 papersNewest fiscal year
P30CA008748Cancer Center Support Grant92025
P30CA016058Cancer Center Support Grant62025
P30CA016056Roswell Park Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant52025
P30CA030199Cancer Center Support Grant (CCSG)42025
R01AG070921Rates and mechanisms of age-related somatic mutation in normal and Alzheimer brain42025
R01NS032457Cell Identity Determination in Human Brain: Somatic Mutation and Cell Lineage42025
P30CA015704Cancer Center Support Grant32025
P30CA042014Cancer Center Support Grant32025
P30DK063491Diabetes Research Center (DRC)32025

1 to 10 of 1,228Source NIH's project files

See all 1,228 nih grants

Papers1,647

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Heterozygous germline mutations in MSH3, and probably MLH3, act as classical tumour suppressors, leading to excess somatic deletion mutations, signature ID4 and increased colorectal cancer risk.Gut202642728028PubTator, text miningPubMed
Divergent somatic mutation patterns among human cerebellar neuron types.Neuron202642575091PubTator, text miningPubMed
GFAP-Dependent Transcriptional Dynamics and Cellular Heterogeneity in Primary, Recurrent, and Grade III Gliomas.Cancer Inform202642368220PubTator, text miningPubMed
Clonal lineage tracing of innate immune cells in human cancer.Cancer Cell202642242233PubTator, text miningPubMed
Single-cell landscape of melanoma reveals ETV5-driven C3 ID4+ tumor subpopulation with extracellular vesicle-associated immunosuppressive and pro-metastatic potential.Front Immunol202642079653PubTator, text miningPubMed
Chemotherapy Enrichment of ID Family Expression Is Associated with IL-6 Signaling in Ovarian Cancer.Cancers (Basel)202642073515PubTator, text miningPubMed
Genomic inversion at 6p22.3 supports ID4 dysregulation as the pathogenic mechanism of Mesomelic dysplasia Savarirayan-type.Eur J Hum Genet202642069959PubTator, text miningPubMed
BMP4 signaling regulates the expression of signals and transcription factors for coordinated cytodifferentiation in the murine ureter.Biochem J202642017529PubTator, text miningPubMed
Matrix-independent quantification of paracetamol in complex aquatic matrices using quadruple isotope dilution Orbitrap mass spectrometry.Talanta202642001727PubTator, text miningPubMed
New Frontiers in the Pathophysiology of Hypertensive Pregnancy Disorders: A Systematic Review of Molecular Insights into Preeclampsia.Curr Issues Mol Biol202641899446PubTator, text miningPubMed

1 to 10 of 1,647

See all 1,647 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3400

GET https://conductscience.org/api/genes/v1/3400/patents?page=2