Gene · 341
APOC1: apolipoprotein C1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. APOC1: apolipoprotein C1. Genes, record 341. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/341
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P02654 | Apolipoprotein C-I | 83 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents97
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 37666 | P02654 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 17610 | P02654 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 952 | P02654 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 953 | P02654 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5504 | P02654 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5504 | P02654 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 17610 | P02654 | Espacenet |
| EP 4549945 A1 | 2025-05-07 | 6 | P02654 | Espacenet |
| JP 2025062601 A | 2025-04-14 | 6 | P02654 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 5709 | P02654 | Espacenet |
1 to 10 of 97
See all 97 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,576
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | APOC1 papers | Newest fiscal year |
|---|---|---|---|
| U24AG021886 | National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) | 34 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 22 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 13 | 2025 |
| U19AG024904 | Alzheimer's Disease Neuroimaging Initiative (ADNI4) | 12 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 11 | 2025 |
| P30DK017047 | Diabetes Research Center | 8 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 7 | 2025 |
| U01AG009740 | Health and Retirement Study: Yrs 35-40 | 7 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 6 | 2025 |
| P30AG034424 | Center for Population Health and Aging | 6 | 2025 |
1 to 10 of 2,576Source NIH's project files
See all 2,576 nih grantsPapers2,927
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Explainable Artificial Intelligence and Gene-Network Analysis Prioritise a TREM2/LGALS3/GPNMB Scar-Associated Macrophage Programme in Human Liver Cirrhosis. | Int J Mol Sci | 2026 | 42794453 | PubTator, text mining | PubMed |
| Maternal and offspring genome-wide association study of C-reactive protein reveals limited polygenic association with gestational diabetes mellitus. | BMC Genomics | 2026 | 42786432 | PubTator, text mining | PubMed |
| Hepatitis B virus proteome analysis identifies apolipoprotein C1 facilitating particle production and virus entry. | Hepatology | 2026 | 42758966 | PubTator, text mining | PubMed |
| APOC1-Associated VLDL-Pathway Dysregulation in Papillary Thyroid Carcinoma: A Reproducible Cross-Cohort Transcriptomic Signature Associated With the Diagnostic-to-Treatment Interval. | Chem Biol Drug Des | 2026 | 42742374 | PubTator, text mining | PubMed |
| Multi-omics mapping of PSC genetic risk to a high TWAS-active JAML+ lipid-associated macrophage program: bridging single-cell heterogeneity, spatial fibrotic niches, and machine learning selection. | Front Cell Dev Biol | 2026 | 42707798 | PubTator, text mining | PubMed |
| Integrated histopathology and single-cell transcriptomics reveal distinct pathological features and foamy macrophage characteristics in spinal tuberculosis and brucellar spondylitis. | Front Immunol | 2026 | 42698543 | PubTator, text mining | PubMed |
| Single-cell RNA sequencing reveals hypoxia-associated stress response signatures in the immune and stromal microenvironment of laryngeal squamous cell carcinoma. | Front Immunol | 2026 | 42614551 | PubTator, text mining | PubMed |
Bioinformatics analysis combined with cell experiments reveals that APOC1 inhibits ferroptosis and promotes M2 macrophage polarization by activating the PI3K/AKT signaling pathway in oral squamous cell carcinoma cells. | Tissue Cell | 2026 | 42594501 | PubTator, text mining | PubMed |
| Common genetic variants in dyslipidemia, inflammation, and angiogenesis pathways associated with diabetic nephropathy in Tunisians. | Endocrine | 2026 | 42573890 | PubTator, text mining | PubMed |
| APOC1 in tumor-associated macrophages enhances protumorigenic M2 polarization and promotes PAAD progression. | Cell Signal | 2026 | 42567335 | PubTator, text mining | PubMed |
1 to 10 of 2,927
See all 2,927 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/341
GET https://conductscience.org/api/genes/v1/341/patents?page=2