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Gene · 3423

IDS: iduronate 2-sulfatase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. IDS: iduronate 2-sulfatase. Genes, record 3423. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3423

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Gene

Symbol
IDS
HGNC
Name
iduronate 2-sulfatase
HGNC
NCBI Gene ID
3423
NCBI Gene
HGNC ID
HGNC:5389
HGNC
Ensembl
ENSG00000010404
NCBI Gene
Aliases
ID2S, MPS2, SIDS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P22304Iduronate 2-sulfatase5502Ensembl, GeneID, HGNC

Source UniProt

Patents275

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4775992 A22026-07-151P22304Espacenet
EP 4775992 A22026-07-1527P22304Espacenet
US 12636363 B22026-05-261P22304Espacenet
JP 2026077678 A2026-05-1391P22304Espacenet
JP 2026067851 A2026-04-21283P22304Espacenet
EP 4650780 A22025-11-196474P22304Espacenet
JP 2025170352 A2025-11-182P22304Espacenet
JP 2025170352 A2025-11-184P22304Espacenet
JP 2025170352 A2025-11-186P22304Espacenet
JP 2025170352 A2025-11-189P22304Espacenet

1 to 10 of 275

See all 275 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants548

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIDS papersNewest fiscal year
R01DK067859Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity172025
R01HD102545Non-invasive functional assessment and pathogenesis of Morquio A42025
ZIATR000018Drug Repurposing Screening for Rare and Neglected Diseases32025
P30CA016058Cancer Center Support Grant22025
P30DK020579Diabetes Research Center22025
R01NS092823The role of a-synuclein accumulation in lysosomal hydrolase trafficking and function22025
T32HL007936Training Program in Translational Cardiovascular Science22025
UL1TR001878Institutional Clinical and Translational Science Award22025
ZIACL080013Molecular and Virulence Traits of Bacteria & Fungi Causing Persistent Infections22025
ZICHL006145NHLBI iPSC Core Facility22025

1 to 10 of 548Source NIH's project files

See all 548 nih grants

Papers1,392

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Development and validation of an ELISA-based assay for detecting anti-idursulfase beta IgE antibodies in human serum using a conjugated IgG-IgE positive control antibody.J Immunol Methods202642767399PubTator, text miningPubMed
Longitudinal Assessment of Cognitive Development in 23 Patients With Mucopolysaccharidosis (MPS) Type II: Results of up to 14 Years of Follow-Up.J Inherit Metab Dis202642723346PubTator, text miningPubMed
Interim analysis of post-marketing surveillance study of intracerebroventricular idursulfase therapy for neuronopathic mucopolysaccharidosis type II: Safety and effectiveness in clinical practice in Japan.
Mol Genet Metab202642679455PubTator, text miningPubMed
Quantum Statistical Behaviors of Carriers in Strong Inversion Layers Associated with Mobility and Threshold Voltage in FinFET Transistors.Micromachines (Basel)202642513019PubTator, text miningPubMed
Sustained clinical benefit of idursulfase beta in mucopolysaccharidosis II: two-year experience from a phase 3 extension study including patients switched from idursulfase.Orphanet J Rare Dis202642421116PubTator, text miningPubMed
Integrative multi-omics analysis identifies a mitochondrial dysfunction-associated diagnostic signature, molecular subtypes, and drug repurposing candidates for keloid disease.Burns202642413388PubTator, text miningPubMed
Tividenofusp Alfa: First Approval.Mol Diagn Ther202642313339PubTator, text miningPubMed
Analytical Validation of MyProstateScore 2.0-Active Surveillance: A Urinary-Based Clinical RT-PCR Prostate Cancer Assay.Diagnostics (Basel)202642196852PubTator, text miningPubMed
Merging evans syndrome with mucopolysaccharidosis type II: a case report.Front Pediatr202642158367PubTator, text miningPubMed
Harmonizing Perspectives on MPS II Care in Türkiye: A Delphi Study Towards Treatment Management Consensus.Healthcare (Basel)202642121657PubTator, text miningPubMed

1 to 10 of 1,392

See all 1,392 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3423

GET https://conductscience.org/api/genes/v1/3423/patents?page=2