Gene · 3425
IDUA: alpha-L-iduronidase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IDUA: alpha-L-iduronidase. Genes, record 3425. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3425
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P35475 | Alpha-L-iduronidase | 653 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents132
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026097826 A | 2026-06-16 | 1 | P35475 | Espacenet |
| JP 2026067851 A | 2026-04-21 | 284 | P35475 | Espacenet |
| EP 4704920 A1 | 2026-03-11 | 141 | P35475 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1231 | P35475 | Espacenet |
| JP 2025169942 A | 2025-11-14 | 1080 | P35475 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 137 | P35475 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 877 | P35475 | Espacenet |
| EP 4641203 A2 | 2025-10-29 | 35 | P35475 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 6718 | P35475 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6642 | P35475 | Espacenet |
1 to 10 of 132
See all 132 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,109
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IDUA papers | Newest fiscal year |
|---|---|---|---|
| R01DK067859 | Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity | 20 | 2025 |
| T32GM008243 | UCLA Medical Genetics Training Program | 11 | 2025 |
| P30AG066444 | Alzheimer's Disease Research Center | 5 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 4 | 2025 |
| P01CA065493 | Off-the-Shelf Immune Effector Cells for Hematological Malignancies | 4 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 4 | 2025 |
| R01HD102545 | Non-invasive functional assessment and pathogenesis of Morquio A | 4 | 2025 |
| UL1TR001881 | UCLA Clinical and Translational Science Institute | 4 | 2025 |
| P01AG026276 | Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study | 3 | 2025 |
| P30AG062422 | New Approaches to Dementia Heterogeneity | 3 | 2025 |
1 to 10 of 1,109Source NIH's project files
See all 1,109 nih grantsPapers1,870
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Unmasking Mucopolysaccharidosis Type I in a Patient With Wolf-Hirschhorn Syndrome: Diagnostic Overshadowing. | JIMD Rep | 2026 | 42707122 | PubTator, text mining | PubMed |
| Early detection in action: developing and refining newborn screening for Pompe disease in North Carolina. | Mol Genet Metab | 2026 | 42691781 | PubTator, text mining | PubMed |
| Multiplex MSMS measurement of lysosomal enzymes enables incidental diagnosis of acid sphingomyelinase deficiency in patients evaluated for Gaucher disease. | Mol Genet Metab | 2026 | 42641356 | PubTator, text mining | PubMed |
| First bone marrow transplantation for mucopolysaccharidosis type I in Vietnam: a case report. | Ther Adv Rare Dis | 2026 | 42553443 | PubTator, text mining | PubMed |
| Proteome-Wide Mendelian Randomization Identifies Causal Proteins for Multiple Sclerosis Susceptibility and Severity. | Genes (Basel) | 2026 | 42510850 | PubTator, text mining | PubMed |
| Identification of genetic variants associated with idiopathic inflammatory myopathies via cross-trait analysis with B cell lymphomas. | HGG Adv | 2026 | 42499187 | PubTator, text mining | PubMed |
| Oral nanoparticle-encapsulated enzyme replacement therapy for mucopolysaccharidosis type I (MPS-I): a proof of concept study. | Drug Deliv Transl Res | 2026 | 42323476 | PubTator, text mining | PubMed |
| Searching for New Genes That Cause Usher Syndrome. | Am J Ophthalmol | 2026 | 42309414 | PubTator, text mining | PubMed |
| Mucopolysaccharidosis type I with retinal degeneration and absence of corneal involvement in the eighth decade of life. | Ophthalmic Genet | 2026 | 42246377 | PubTator, text mining | PubMed |
| Variant classification for mucopolysaccharidosis type I; ACMG/AMP specification for IDUA from the ClinGen lysosomal diseases variant curation expert panel. | Mol Genet Metab | 2026 | 42190545 | PubTator, text mining | PubMed |
1 to 10 of 1,870
See all 1,870 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3425
GET https://conductscience.org/api/genes/v1/3425/patents?page=2