Gene · 3426
CFI: complement factor I
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CFI: complement factor I. Genes, record 3426. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3426
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P05156 | Complement factor I | 583 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents94
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026120564 A | 2026-07-22 | 1 | P05156 | Espacenet |
| JP 2026041876 A | 2026-03-10 | 1 | P05156 | Espacenet |
| US 12544423 B2 | 2026-02-10 | 25 | P05156 | Espacenet |
| JP 2026501750 A | 2026-01-16 | 35 | P05156 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 42135 | P05156 | Espacenet |
| WO 2025262255 A1 | 2025-12-26 | 39 | P05156 | Espacenet |
| WO 2025253101 A1 | 2025-12-11 | 15 | P05156 | Espacenet |
| JP 2025539119 A | 2025-12-03 | 14 | P05156 | Espacenet |
| KR 1020250163297 A | 2025-11-20 | 35 | P05156 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 11165 | P05156 | Espacenet |
1 to 10 of 94
See all 94 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,574
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CFI papers | Newest fiscal year |
|---|---|---|---|
| R01DK110023 | C3 Glomerulopathy -- A Collaborative Study | 12 | 2025 |
| ZIAEY000489 | Age-Related Eye Disease Follow-up Study (AREDS) Follow-up Study | 8 | 2025 |
| ZIAEY000546 | Mechanisms, modeling and therapies of retinal and macular neurodegeneration | 8 | 2025 |
| P30AI064518 | Center for AIDS Research | 7 | 2025 |
| P30EY014800 | University of Utah Core Vision Research Grant | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30EY005722 | Center Core Grant for Vision Research | 6 | 2025 |
| UM1AI068618 | HIV Vaccine Trials Network Laboratory Center | 6 | 2025 |
| K12EY016335 | Harvard-Vision Clinical Scientist Development Program | 5 | 2025 |
| P30AI060354 | Harvard University Center for AIDS Research | 5 | 2025 |
1 to 10 of 1,574Source NIH's project files
See all 1,574 nih grantsPapers3,374
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Network Analysis of Cognitive Flexibility, Emotion Regulation, and Symptom Severity in Patients with Major Depression. | Psychiatr Q | 2026 | 42804067 | PubTator, text mining | PubMed |
| Development and validation of a machine learning-based claims frailty index for predicting mortality, disability, and healthcare utilization in middle-aged and older adults. | Exp Gerontol | 2026 | 42785600 | PubTator, text mining | PubMed |
| Kidney transplant outcomes in patients with complement dysregulation. | World J Transplant | 2026 | 42751233 | PubTator, text mining | PubMed |
| Complement expression profiles in human glomerular mesangial cells, endothelial cells, podocytes and proximal tubular epithelial cells. | Front Immunol | 2026 | 42746023 | PubTator, text mining | PubMed |
| Genetic insights into lung squamous cell carcinoma: how TP53 and CSMD3 co-mutations shape prognosis and immune response. | Transl Cancer Res | 2026 | 42724489 | PubTator, text mining | PubMed |
| Artificial intelligence for precision therapeutics in age-related macular degeneration: current advances, challenges, and future directions. | Front Artif Intell | 2026 | 42676384 | PubTator, text mining | PubMed |
| Systemic and local dysregulation of the complement system in glioma: a comprehensive systematic review. | Clin Transl Oncol | 2026 | 42627589 | PubTator, text mining | PubMed |
| Biomarker-Informed Interpretation of Dyadic Cognitive Function Index Scores in Cognitively Unimpaired Older Adults. | medRxiv | 2026 | 42619894 | PubTator, text mining | PubMed |
| Genetic susceptibility to thrombotic microangiopathy in a 10-month-old patient with SMA type 1: a caveat for gene therapy eligibility. | Neuromuscul Disord | 2026 | 42612481 | PubTator, text mining | PubMed |
| Prospective associations of tea consumption with skeletal muscle mass and strength: Insights from the gut microbiome and proteomics. | Pharmacol Res | 2026 | 42600761 | PubTator, text mining | PubMed |
1 to 10 of 3,374
See all 3,374 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3426
GET https://conductscience.org/api/genes/v1/3426/patents?page=2