Gene · 3428
IFI16: interferon gamma inducible protein 16
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IFI16: interferon gamma inducible protein 16. Genes, record 3428. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3428
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16666 | Gamma-interferon-inducible protein 16 | 785 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents30
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 50087 | Q16666 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3246 | Q16666 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15161 | Q16666 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3246 | Q16666 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15161 | Q16666 | Espacenet |
| EP 4502181 A1 | 2025-02-05 | 13 | Q16666 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15161 | Q16666 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15000 | Q16666 | Espacenet |
| JP 2024522216 A | 2024-06-11 | 112 | Q16666 | Espacenet |
| KR 1020240022540 A | 2024-02-20 | 112 | Q16666 | Espacenet |
1 to 10 of 30
See all 30 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,060
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IFI16 papers | Newest fiscal year |
|---|---|---|---|
| P01CA019014 | Viral Oncogenesis, Latency, and Replication | 12 | 2025 |
| P30AG017265 | USC/UCLA Center on Biodemography and Population Health | 9 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 7 | 2025 |
| R01AI124346 | Innate immune signaling and stress response | 7 | 2025 |
| R37AI101935 | Inflammatory Caspases in Innate Immunity and Inflammation | 7 | 2025 |
| T32AI095213 | Innate Immunity Training Program | 7 | 2025 |
1 to 10 of 2,060Source NIH's project files
See all 2,060 nih grantsPapers2,876
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Age as a biological stratifier for immune checkpoint inhibitor response in ovarian cancer. | Res Sq | 2026 | 42779970 | PubTator, text mining | PubMed |
| Multi-omics analysis identifies macrophage immunometabolic signatures in ulcerative colitis. | Front Cell Infect Microbiol | 2026 | 42755516 | PubTator, text mining | PubMed |
| Integrated multi-omics profiling identifies aging-related molecular signatures and convergent interferon signaling in systemic lupus erythematosus. | Front Immunol | 2026 | 42688381 | PubTator, text mining | PubMed |
| Cell death network regulation in HSV infection: immune evasion versus host defense. | Apoptosis | 2026 | 42671474 | PubTator, text mining | PubMed |
| [Exploring the impact of macrophage depletion on influenza viral pneumonia and its mechanism of action through the cGAS-STING pathway]. | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | 2026 | 42634902 | PubTator, text mining | PubMed |
| Doxorubicin-induced damage to AC16 cardiomyocytes and attenuation by human pericardial fluid Sca-1+/Nanog+ cells conditioned medium: a pilot study. | Biochim Biophys Acta Gen Subj | 2026 | 42612758 | PubTator, text mining | PubMed |
| RADX protects against intestinal inflammation by restraining IFI16-mediated innate immunity. | EMBO Mol Med | 2026 | 42498843 | PubTator, text mining | PubMed |
| Transcriptomics, lifestyle, and autoimmune thyroiditis: an integrated association study. | Front Immunol | 2026 | 42421942 | PubTator, text mining | PubMed |
| Endosymbiotic theory of aging revisited: Age-related leakage of mitochondrial dsDNA/RNA stimulates cytosolic nucleic acid sensors which remodel the immune network and promote the aging process. | Biogerontology | 2026 | 42412246 | PubTator, text mining | PubMed |
| Discovery of Potential New Drug Targets for Osteoporosis of Various Subtypes With or Without Pathological Fracture Complications: A Drug Target Mendelian Randomization Study. | Geriatr Gerontol Int | 2026 | 42366925 | PubTator, text mining | PubMed |
1 to 10 of 2,876
See all 2,876 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3428
GET https://conductscience.org/api/genes/v1/3428/patents?page=2