Gene · 3437
IFIT3: interferon induced protein with tetratricopeptide repeats 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IFIT3: interferon induced protein with tetratricopeptide repeats 3. Genes, record 3437. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3437
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O14879 | Interferon-induced protein with tetratricopeptide repeats 3 | 490 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents94
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2025252547 A1 | 2025-12-11 | 52 | O14879 | Espacenet |
| EP 4660322 A1 | 2025-12-10 | 52 | O14879 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9013 | O14879 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9015 | O14879 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5528 | O14879 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5529 | O14879 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9013 | O14879 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9015 | O14879 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5528 | O14879 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5529 | O14879 | Espacenet |
1 to 10 of 94
See all 94 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,742
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IFIT3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 14 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 11 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 8 | 2025 |
| P51OD010425 | Washington National Primate Research Center | 8 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 8 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 7 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 7 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 6 | 2025 |
1 to 10 of 2,742Source NIH's project files
See all 2,742 nih grantsPapers3,172
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| SIRT1-mediated deacetylation of TRIM21 promotes IRF5 degradation and restrains type I interferon signatures in Sjögren's disease. | Transl Res | 2026 | 42778089 | PubTator, text mining | PubMed |
| Transcriptomic signatures of mind-body transformations therapy in breast cancer: Downregulation of the interferon signaling pathway. | Breast | 2026 | 42748847 | PubTator, text mining | PubMed |
| Identification of STAT1 as a biomarker for lymph node metastasis in esophageal squamous cell carcinoma. | J Mol Histol | 2026 | 42700277 | PubTator, text mining | PubMed |
| Role of IFIT1 and IFIT3 in systemic lupus erythematosus: modeling a diagnosis and exploring immune regulation. | Clin Exp Med | 2026 | 42678612 | PubTator, text mining | PubMed |
| Interferon-stimulated gene signature predicts clinical response to low-dose IL-2 in immune-mediated inflammatory diseases. | Ann Rheum Dis | 2026 | 42618420 | PubTator, text mining | PubMed |
| Systems-level insights into age-dependent innate immune responses in influenza B infection. | Microbiol Spectr | 2026 | 42615604 | PubTator, text mining | PubMed |
| IFIT3 silencing improves the sensitivity of gliomas to temozolomide by inactivating the PI3K/AKT signaling pathway. | Behav Brain Res | 2026 | 42603632 | PubTator, text mining | PubMed |
| Interferon-Associated Antiviral Programs Define LAG-3+ Exhaustion-Like CD8+ T-Cell Remodeling in Influenza a Virus Infection: An Integrative Single-Cell and Multi-Cohort Analysis. | Immunol Invest | 2026 | 42533594 | PubTator, text mining | PubMed |
| MX2 and IRF7 are Associated With Disease Activity and Renal Involvement in Systemic Lupus Erythematosus: An Exploratory Study. | J Immunol Res | 2026 | 42504115 | PubTator, text mining | PubMed |
| Multiparametric flow cytometry immune profiling of pulmonary and extra-pulmonary tuberculosis reveals distinct blood-based biomarker signatures. | Tuberculosis (Edinb) | 2026 | 42501466 | PubTator, text mining | PubMed |
1 to 10 of 3,172
See all 3,172 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3437
GET https://conductscience.org/api/genes/v1/3437/patents?page=2