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IFNA1: interferon alpha 1

1 protein, 173 patents, 3 drugs, 10 trials, 23,648 NIH grants and 76,577 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIFNA1HGNC
Nameinterferon alpha 1HGNC
NCBI Gene ID3439NCBI Gene
HGNC IDHGNC:5417HGNC
EnsemblENSG00000197919NCBI Gene
AliasesIFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@, leIF DNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P0DY56Interferon alpha-11891Ensembl, GeneID, HGNCUniProt

Patents 173

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026164090 A2026-08-061P0DY56Espacenet
EP 4724500 A22026-04-15417P0DY56Espacenet
EP 4705273 A22026-03-11530P0DY56Espacenet
EP 4705483 A12026-03-118P0DY56Espacenet
EP 4698234 A22026-02-255P0DY56Espacenet
JP 2026000906 A2026-01-0613P0DY56Espacenet
EP 4650780 A22025-11-192984P0DY56Espacenet
EP 4627095 A22025-10-085P0DY56Espacenet
JP 2025147176 A2025-10-066725P0DY56Espacenet
JP 2025147176 A2025-10-0616729P0DY56Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
FARALIMOMABCHEMBL2108407Interferon alpha-1/13 binding agentBINDING AGENTChEMBL
RONTALIZUMABCHEMBL1743066Interferon alpha inhibitorINHIBITORChEMBL
SIFALIMUMABCHEMBL1743069Interferon alpha inhibitorINHIBITORChEMBL

Trials 10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01283139SIFALIMUMABPHASE22016-07-11ClinicalTrials.gov
NCT01031836SIFALIMUMABPHASE22018-11-19ClinicalTrials.gov
NCT00979654SIFALIMUMABPHASE22016-08-23ClinicalTrials.gov
NCT00962832RONTALIZUMABPHASE2ClinicalTrials.gov
NCT00657189SIFALIMUMABPHASE2ClinicalTrials.gov
NCT00541749RONTALIZUMABPHASE1ClinicalTrials.gov
NCT00533091SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00482989SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00472758SIFALIMUMABPHASE1ClinicalTrials.gov
NCT00299819SIFALIMUMABPHASE1ClinicalTrials.gov

NIH grants 23648

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2432,025NIH's project files
P30CA016672Cancer Center Support Grant2422,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award1052,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success1042,025NIH's project files
P30CA047904Cancer Center Support Grant832,025NIH's project files
P51OD011132Emory National Primate Research Center822,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program762,025NIH's project files
P30CA016058Cancer Center Support Grant712,025NIH's project files
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro592,025NIH's project files
U19AI082630Durable Alteration of the Human Immune system after Infection or Immunotherapy542,025NIH's project files

Papers 76577

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826657PubTator, text miningPubMed
42825488PubTator, text miningPubMed
42818629PubTator, text miningPubMed
42818302PubTator, text miningPubMed
42818208PubTator, text miningPubMed
42815867PubTator, text miningPubMed
42813001PubTator, text miningPubMed
42812250PubTator, text miningPubMed
42811238PubTator, text miningPubMed
42810773PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license