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Gene · 344

APOC2: apolipoprotein C2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. APOC2: apolipoprotein C2. Genes, record 344. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/344

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Gene

Symbol
APOC2
HGNC
Name
apolipoprotein C2
HGNC
NCBI Gene ID
344
NCBI Gene
HGNC ID
HGNC:609
HGNC
Ensembl
ENSG00000234906
NCBI Gene
Aliases
APO-CII, APOC-II
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P02655Apolipoprotein C-II1014Ensembl, GeneID, HGNC

Source UniProt

Patents75

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437667P02655Espacenet
EP 4650780 A22025-11-191390P02655Espacenet
EP 4641201 A22025-10-291025P02655Espacenet
JP 2025147176 A2025-10-06960P02655Espacenet
JP 2025147176 A2025-10-06961P02655Espacenet
JP 2025529142 A2025-09-045505P02655Espacenet
US 12371689 B22025-07-295505P02655Espacenet
JP 2025517969 A2025-06-121025P02655Espacenet
JP 2025517970 A2025-06-121390P02655Espacenet
JP 2025062604 A2025-04-145650P02655Espacenet

1 to 10 of 75

See all 75 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,673

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAPOC2 papersNewest fiscal year
P30DK017047Diabetes Research Center132025
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)82025
P01HL151328Triglycerides, Diabetes and Cardiovascular Disease52025
P30CA016672Cancer Center Support Grant52025
P30DK063491Diabetes Research Center (DRC)52025
R01GM135158Structure and Function of Serum Amyloid A in Health and Disease52025
ZIAHL006095Development of Apo Mimetic Peptides for the Treatment Cardiovascular Disease52025
P30DK020593Vanderbilt Diabetes Research Center42025
P30DK035816Nutrition Obesity Research Center42025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)42025

1 to 10 of 1,673Source NIH's project files

See all 1,673 nih grants

Papers3,206

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Single-cell profiling and genetic regulation of alternative polyadenylation in the human brain.Nat Genet202642816601PubTator, text miningPubMed
Plasma proteomic profiling of septic shock and acute pancreatitis identifies shared signatures and disease-specific pathways.Sci Rep202642702635PubTator, text miningPubMed
The role of genetic variation in apolipoprotein response to diet among Brazilians with cardiovascular disease.Eur J Clin Nutr202642557382PubTator, text miningPubMed
Clinicopathological characteristics and prognostic factors in renal amyloidosis: a 10-year Australian tertiary centre experience.Pathology202642557181PubTator, text miningPubMed
Utility of clinical scoring systems, laboratory, and genetic testing for appropriate classification of patients with severe hypertriglyceridemia in a Latin American cohort.J Clin Lipidol202642527267PubTator, text miningPubMed
Untargeted LC-MS/MS profiling identifies ST18 as a novel serum marker for T2DM-associated depression.Ann Clin Biochem202642493251PubTator, text miningPubMed
Association of APOC2 upstream variant rs10425530 with BMI predicted to overlap with NR2C2, GCM2 and NR2C1 binding sites.Hum Genomics202642482148PubTator, text miningPubMed
Serum TNF-α, oxidized LDL, and APOCII as novel predictors for familial mediterranean fever in Egyptian children: a cross-sectional study.J Complement Integr Med202642459057PubTator, text miningPubMed
Deep Proteomic Analysis With Machine Learning Identifies Aqueous Humor Biomarkers of ADAMTSL4-associated Congenital Ectopia Lentis.Invest Ophthalmol Vis Sci202642423409PubTator, text miningPubMed
Longitudinal Cognitive Evolution in Alcohol Use Disorder Patients: Role of Inflammation, Time of Abstinence and Apolipoprotein Profile.Addict Biol202642386626PubTator, text miningPubMed

1 to 10 of 3,206

See all 3,206 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/344

GET https://conductscience.org/api/genes/v1/344/patents?page=2