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IFNA2: interferon alpha 2

1 protein, 272 patents, 3 drugs, 16 trials, 4,816 NIH grants and 18,273 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolIFNA2HGNC
Nameinterferon alpha 2HGNC
NCBI Gene ID3440NCBI Gene
HGNC IDHGNC:5423HGNC
EnsemblENSG00000188379NCBI Gene
AliasesIFN-alpha-2, IFN-alphaA, IFNA, IFNA2B, leIF ANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01563Interferon alpha-218813Ensembl, GeneID, HGNCUniProt

Patents 272

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026213183 A12026-10-081P01563Espacenet
EP 4774003 A12026-07-154P01563Espacenet
US 12653852 B22026-06-1642P01563Espacenet
EP 4740966 A12026-05-13175P01563Espacenet
EP 4724500 A22026-04-15418P01563Espacenet
WO 2025247913 A12025-12-043P01563Espacenet
WO 2025247917 A12025-12-043P01563Espacenet
WO 2025247918 A12025-12-043P01563Espacenet
WO 2025247924 A12025-12-043P01563Espacenet
JP 2025538568 A2025-11-285P01563Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
NADOFARAGENE FIRADENOVECCHEMBL3990041Interferon alpha-2 exogenous geneEXOGENOUS GENEChEMBL
RONTALIZUMABCHEMBL1743066Interferon alpha inhibitorINHIBITORChEMBL
SIFALIMUMABCHEMBL1743069Interferon alpha inhibitorINHIBITORChEMBL

Trials 16

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07332351NADOFARAGENE FIRADENOVECPHASE2ClinicalTrials.gov
NCT07189195NADOFARAGENE FIRADENOVECPHASE1ClinicalTrials.gov
NCT06668493NADOFARAGENE FIRADENOVECPHASE1/PHASE2ClinicalTrials.gov
NCT06545955NADOFARAGENE FIRADENOVECPHASE3ClinicalTrials.gov
NCT03710876NADOFARAGENE FIRADENOVECPHASE32025-05-20ClinicalTrials.gov
NCT02773849NADOFARAGENE FIRADENOVECPHASE32022-07-13ClinicalTrials.gov
NCT01283139SIFALIMUMABPHASE22016-07-11ClinicalTrials.gov
NCT01031836SIFALIMUMABPHASE22018-11-19ClinicalTrials.gov
NCT00979654SIFALIMUMABPHASE22016-08-23ClinicalTrials.gov
NCT00962832RONTALIZUMABPHASE2ClinicalTrials.gov

NIH grants 4816

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success692,025NIH's project files
P30CA016672Cancer Center Support Grant562,025NIH's project files
P30CA008748Cancer Center Support Grant362,025NIH's project files
R01AI163029Inborn errors of immunity in patients with life-threatening COVID-19332,025NIH's project files
P30CA013330Cancer Center Support Grant242,025NIH's project files
ZIADK075009Natural History, Therapy and Pathogenesis of Chronic Viral Hepatitis C242,025NIH's project files
P30CA047904Cancer Center Support Grant232,025NIH's project files
P30CA016058Cancer Center Support Grant212,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award182,025NIH's project files
P51OD011132Emory National Primate Research Center172,025NIH's project files

Papers 18273

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42796880PubTator, text miningPubMed
42789737PubTator, text miningPubMed
42752598PubTator, text miningPubMed
42747404PubTator, text miningPubMed
42742095PubTator, text miningPubMed
42738824PubTator, text miningPubMed
42736283PubTator, text miningPubMed
42703000PubTator, text miningPubMed
42700226PubTator, text miningPubMed
42655973PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license